Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SON02_RS06735 Genome accession   NZ_CP139211
Coordinates   1532728..1533930 (+) Length   400 a.a.
NCBI ID   WP_135028775.1    Uniprot ID   -
Organism   Streptococcus sp. LysM4     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1527728..1538930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SON02_RS06730 (SON02_06715) - 1528384..1532238 (+) 3855 WP_410531151.1 SpaA isopeptide-forming pilin-related protein -
  SON02_RS06735 (SON02_06720) cinA 1532728..1533930 (+) 1203 WP_135028775.1 competence/damage-inducible protein A Machinery gene
  SON02_RS06740 (SON02_06725) recA 1533966..1535111 (+) 1146 WP_135028777.1 recombinase RecA Machinery gene
  SON02_RS06745 (SON02_06730) spx 1535313..1535711 (+) 399 WP_075099515.1 transcriptional regulator Spx -
  SON02_RS06750 (SON02_06735) - 1535898..1536164 (+) 267 WP_135028779.1 IreB family regulatory phosphoprotein -
  SON02_RS06755 (SON02_06740) ruvX 1536164..1536583 (+) 420 WP_135028781.1 Holliday junction resolvase RuvX -
  SON02_RS06760 (SON02_06745) - 1536594..1536905 (+) 312 WP_135028784.1 DUF1292 domain-containing protein -
  SON02_RS06765 (SON02_06750) comR 1537974..1538885 (+) 912 WP_135028786.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 43567.14 Da        Isoelectric Point: 5.0538

>NTDB_id=908064 SON02_RS06735 WP_135028775.1 1532728..1533930(+) (cinA) [Streptococcus sp. LysM4]
MKAELIAVGTEILTGQIVNTNAQFLSEKFAEMGIDVFFHTAVGDNETRLLSVLDIASKRSDLVVLCGGLGPTEDDLTKQT
LAIFLGKELVFDQVALDKLDRFFASRKGRIRTPNNERQAQLVKGSTALHNPAGLAVGGLIEQDGVTYIVLPGPPSELKAM
FTESLQPLLVHSSEKLYSRILRFFGIGESQLVSILADLIENQTDPTLAPYAKIGEVTLRLSTKAEEEATANQKLNQLEQA
ILAREHLATCLYGYGEDNSLSRIVARELEVQGISFAVVENVTAGALQADLTLALHSCHLFAGGLVVRDEMITAKRAEELS
RFICKDLEAGLGLALLGQVKPESQIDNVVASYFIAICLNGQVTVTEVDLGGYTEQHMRHIACLHALNVMRNILSNRKVLL

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=908064 SON02_RS06735 WP_135028775.1 1532728..1533930(+) (cinA) [Streptococcus sp. LysM4]
ATGAAAGCAGAGTTGATTGCAGTTGGGACTGAAATTTTGACAGGGCAAATCGTGAACACCAATGCTCAATTTTTATCGGA
AAAATTTGCCGAAATGGGTATAGATGTCTTTTTCCATACCGCAGTGGGAGATAATGAAACGCGCCTCTTGTCTGTTTTAG
ATATTGCTAGTAAGCGCAGTGATTTGGTTGTTCTCTGCGGTGGATTAGGACCGACTGAAGATGATTTAACAAAACAAACG
TTGGCCATTTTTTTAGGGAAAGAATTGGTCTTTGACCAGGTGGCCTTGGATAAATTAGACCGCTTTTTTGCAAGCAGAAA
AGGTCGGATTCGGACTCCGAATAATGAACGACAAGCCCAGTTAGTAAAAGGAAGTACCGCACTCCACAATCCAGCAGGTC
TAGCAGTGGGTGGTTTGATTGAGCAGGATGGTGTGACTTATATTGTCTTGCCTGGTCCGCCTAGCGAATTAAAGGCCATG
TTTACAGAAAGTTTACAGCCGTTGCTAGTTCATTCAAGCGAGAAATTGTACTCTCGCATTCTACGATTTTTTGGAATTGG
TGAAAGTCAGTTGGTAAGCATTTTAGCTGATTTAATTGAAAATCAGACAGATCCAACTTTGGCACCTTATGCCAAGATAG
GAGAGGTTACCTTGCGTCTATCTACAAAGGCTGAAGAGGAAGCCACAGCCAATCAGAAATTAAATCAATTAGAGCAAGCA
ATCCTAGCTCGAGAACACCTTGCTACGTGCTTATATGGATATGGTGAAGATAATAGTTTATCTAGGATTGTAGCTCGTGA
ATTAGAAGTACAGGGTATTAGCTTTGCAGTTGTAGAAAATGTAACGGCTGGAGCATTGCAAGCTGACTTGACACTTGCTT
TACACAGTTGTCACCTATTTGCAGGTGGTTTAGTTGTTAGAGATGAGATGATAACTGCTAAAAGAGCAGAGGAGCTGTCA
CGTTTTATATGTAAAGACCTAGAAGCAGGTTTAGGTCTAGCCCTGTTAGGGCAAGTAAAGCCAGAATCTCAGATTGATAA
TGTTGTGGCAAGCTATTTTATTGCTATTTGTTTGAATGGTCAAGTGACAGTCACGGAAGTTGATTTAGGTGGTTATACAG
AACAACACATGCGTCACATTGCTTGTTTACATGCCTTGAATGTTATGCGTAATATTTTGTCAAACCGTAAAGTTTTGCTA
TAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

65.394

98.25

0.642
  cinA Streptococcus mitis NCTC 12261

56.01

100

0.583
  cinA Streptococcus mitis SK321

56.01

100

0.583
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.58
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.58
  cinA Streptococcus pneumoniae R6

55.769

100

0.58
  cinA Streptococcus pneumoniae D39

55.529

100

0.578
  cinA Streptococcus mutans UA159

53.207

100

0.56
  cinA Bacillus subtilis subsp. subtilis str. 168

41.944

97.75

0.41