Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   R2E40_RS20335 Genome accession   NZ_CP137631
Coordinates   4367429..4368670 (+) Length   413 a.a.
NCBI ID   WP_286041689.1    Uniprot ID   -
Organism   Aeromonas sp. CD     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4362429..4373670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2E40_RS20310 (R2E40_20310) ampD 4362746..4363318 (-) 573 WP_202003185.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  R2E40_RS20315 (R2E40_20315) - 4363466..4363936 (+) 471 WP_318164255.1 retropepsin-like aspartic protease -
  R2E40_RS20320 (R2E40_20320) nadC 4363942..4364799 (+) 858 WP_318164256.1 carboxylating nicotinate-nucleotide diphosphorylase -
  R2E40_RS20325 (R2E40_20325) tapA 4365122..4365604 (+) 483 WP_318164257.1 type IVa pilus major pilin TapA -
  R2E40_RS20330 (R2E40_20330) pilB 4365598..4367313 (+) 1716 WP_318164258.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  R2E40_RS20335 (R2E40_20335) pilC 4367429..4368670 (+) 1242 WP_286041689.1 type II secretion system F family protein Machinery gene
  R2E40_RS20340 (R2E40_20340) pilD 4368693..4369565 (+) 873 WP_065392462.1 prepilin peptidase Machinery gene
  R2E40_RS20345 (R2E40_20345) coaE 4369585..4370199 (+) 615 WP_318164259.1 dephospho-CoA kinase -
  R2E40_RS20350 (R2E40_20350) zapD 4370237..4370959 (+) 723 WP_024945431.1 cell division protein ZapD -
  R2E40_RS20355 (R2E40_20355) yacG 4370969..4371163 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  R2E40_RS20360 (R2E40_20360) mutT 4371224..4371637 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  R2E40_RS20365 (R2E40_20365) - 4371646..4372830 (-) 1185 WP_318164260.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45445.61 Da        Isoelectric Point: 9.8638

>NTDB_id=899563 R2E40_RS20335 WP_286041689.1 4367429..4368670(+) (pilC) [Aeromonas sp. CD]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQHWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=899563 R2E40_RS20335 WP_286041689.1 4367429..4368670(+) (pilC) [Aeromonas sp. CD]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTAAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAAATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCGCTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAATCCGGCGCCCTGGAGACCATCTACGATCGCATC
GCTACCTATCGCGAGAAATCGGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTTTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTTACCTCTATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGCGCCGAGC
TGCCCATCTTCACCCAGTTTGTCATCGGCATCTCCCGTTTCATGCAGCATTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATATTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACCACCTTCTCTGCCGGTA
TCCCGCTGGTGGATGCCTTGGTTTCTGCAGCTGGCGCCTCCGGCAACTATGTCTACCGCACCGCTGTCATGGCCATTCGT
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTAGTGTTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCT
ATGTATCTGCCCATCTTCAAACTGGGGTCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.096

96.126

0.443
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366