Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   R5H38_RS00405 Genome accession   NZ_CP137602
Coordinates   70586..71767 (+) Length   393 a.a.
NCBI ID   WP_217374496.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 221006     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 65586..76767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5H38_RS00390 mutL 66587..68524 (+) 1938 WP_318150998.1 DNA mismatch repair endonuclease MutL -
  R5H38_RS00395 ruvA 68770..69360 (+) 591 WP_289646189.1 Holliday junction branch migration protein RuvA -
  R5H38_RS00400 - 69980..70549 (+) 570 WP_217374495.1 DNA-3-methyladenine glycosylase I -
  R5H38_RS00405 cinA 70586..71767 (+) 1182 WP_217374496.1 competence/damage-inducible protein A Machinery gene
  R5H38_RS00410 recA 71819..72973 (+) 1155 WP_172036461.1 recombinase RecA Machinery gene
  R5H38_RS00415 spx 73187..73585 (+) 399 WP_217374497.1 transcriptional regulator Spx -
  R5H38_RS00420 - 73695..73961 (+) 267 WP_130554425.1 IreB family regulatory phosphoprotein -
  R5H38_RS00425 ruvX 73961..74380 (+) 420 WP_277837253.1 Holliday junction resolvase RuvX -
  R5H38_RS00430 - 74392..74712 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  R5H38_RS00435 - 74965..75105 (+) 141 Protein_66 ISL3 family transposase -
  R5H38_RS00440 - 75135..75683 (+) 549 WP_277837254.1 nucleotidyltransferase family protein -
  R5H38_RS00445 comX/sigX 75868..76338 (+) 471 WP_277837255.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42726.70 Da        Isoelectric Point: 4.4569

>NTDB_id=899213 R5H38_RS00405 WP_217374496.1 70586..71767(+) (cinA) [Streptococcus parasuis strain 221006]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVVDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTIAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEKKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=899213 R5H38_RS00405 WP_217374496.1 70586..71767(+) (cinA) [Streptococcus parasuis strain 221006]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATCGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACCAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGTTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGCGGATTTGATTGACAAGCAGACAGACCCGACTATTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTATCTACAAAGGCAGATAGCCAGGAAGAAGCGAACGTTCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGACAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAAAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCAGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCTAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

55.048

100

0.583
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.474

100

0.58
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

47.869

77.608

0.372