Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   M2Z51_RS02465 Genome accession   NZ_AP024967
Coordinates   520991..522217 (-) Length   408 a.a.
NCBI ID   WP_248532072.1    Uniprot ID   -
Organism   Vibrio cholerae strain V130003     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 515991..527217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Z51_RS02445 (V130003_04760) yacG 518342..518539 (-) 198 WP_000162863.1 DNA gyrase inhibitor YacG -
  M2Z51_RS02450 (V130003_04770) zapD 518681..519421 (-) 741 WP_000207194.1 cell division protein ZapD -
  M2Z51_RS02455 (V130003_04780) coaE 519453..520061 (-) 609 WP_248532070.1 dephospho-CoA kinase -
  M2Z51_RS02460 (V130003_04790) pilD 520058..520933 (-) 876 WP_248532071.1 A24 family peptidase Machinery gene
  M2Z51_RS02465 (V130003_04800) pilC 520991..522217 (-) 1227 WP_248532072.1 type II secretion system F family protein Machinery gene
  M2Z51_RS02470 (V130003_04810) pilB 522260..523948 (-) 1689 WP_153733690.1 type IV-A pilus assembly ATPase PilB Machinery gene
  M2Z51_RS02475 (V130003_04820) pilA 523953..524363 (-) 411 WP_148525586.1 pilin Machinery gene
  M2Z51_RS02480 (V130003_04830) nadC 524608..525498 (-) 891 WP_153733689.1 carboxylating nicotinate-nucleotide diphosphorylase -
  M2Z51_RS02485 (V130003_04840) ampD 525796..526341 (+) 546 WP_000567314.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  M2Z51_RS02490 (V130003_04850) fldB 526491..527009 (-) 519 WP_000690112.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45088.35 Da        Isoelectric Point: 10.3424

>NTDB_id=89786 M2Z51_RS02465 WP_248532072.1 520991..522217(-) (pilC) [Vibrio cholerae strain V130003]
MKATQTLPLKNYRWKGINSNGKKVSGQILAISEIEVRDKLKDQHIQIKKLKKGSVSLLARLTHRVKSKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFESAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=89786 M2Z51_RS02465 WP_248532072.1 520991..522217(-) (pilC) [Vibrio cholerae strain V130003]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGCCA
GATACTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTATTGGCGCGCCTAACCCATCGCGTGAAAAGCAAAGACATCACGATTTTGACTCGGCAGTTAGCGACCATG
CTCACCACGGGCGTACCGATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATCACCAAAAGCGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGTACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAGGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAGCTACGCGCTAAGGTGATCAAAGCGCTCATTTACCCCAGTATGGTGGTGTTGGTCGCGCTCGGAGTTTC
CTACTTAATGCTCACCATGGTCATCCCAGAGTTTGAAAGCATGTTTAAAGGCTTTGGTGCCGAGCTGCCTTGGTTTACGC
AGCAAGTGCTGAAACTCTCACACTGGGTGCAGGCTTACAGTTTATGGGCATTTATCGCCATCGCTGCGGCCATTTTTGGC
TTGAAAGCGCTACGTAAAAACTCCTTCCAGATCCGTTTAAAAACCAGTCGATTAGGGCTGAAATTTCCGATTATTGGTAA
TGTGCTCGCTAAGGCTTCCATCGCCAAATTCAGCCGCACCCTCGCCACCAGCTTTGCCGCGGGGATCCCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAAGCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCCGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCAGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACGGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTCTTTCTTGGGACGGTTGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.265

100

0.993
  pilC Vibrio campbellii strain DS40M4

73.75

98.039

0.723
  pilC Acinetobacter baumannii D1279779

42.647

100

0.426
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.462

97.549

0.414
  pilC Pseudomonas stutzeri DSM 10701

42.424

97.059

0.412
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4

Multiple sequence alignment