Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   R2X36_RS19020 Genome accession   NZ_CP137009
Coordinates   4106320..4107561 (+) Length   413 a.a.
NCBI ID   WP_043133310.1    Uniprot ID   -
Organism   Aeromonas media strain QST31     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4101320..4112561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2X36_RS18995 (R2X36_18995) ampD 4101678..4102250 (-) 573 WP_317841573.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  R2X36_RS19000 (R2X36_19000) - 4102396..4102857 (+) 462 WP_374393893.1 TIGR02281 family clan AA aspartic protease -
  R2X36_RS19005 (R2X36_19005) nadC 4102861..4103724 (+) 864 WP_317841574.1 carboxylating nicotinate-nucleotide diphosphorylase -
  R2X36_RS19010 (R2X36_19010) - 4104037..4104480 (+) 444 WP_317841575.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  R2X36_RS19015 (R2X36_19015) pilB 4104484..4106190 (+) 1707 WP_218410023.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  R2X36_RS19020 (R2X36_19020) pilC 4106320..4107561 (+) 1242 WP_043133310.1 type II secretion system F family protein Machinery gene
  R2X36_RS19025 (R2X36_19025) pilD 4107642..4108514 (+) 873 WP_042649027.1 A24 family peptidase Machinery gene
  R2X36_RS19030 (R2X36_19030) coaE 4108533..4109147 (+) 615 WP_317841576.1 dephospho-CoA kinase -
  R2X36_RS19035 (R2X36_19035) zapD 4109185..4109907 (+) 723 WP_226170498.1 cell division protein ZapD -
  R2X36_RS19040 (R2X36_19040) yacG 4109917..4110111 (+) 195 WP_042649030.1 DNA gyrase inhibitor YacG -
  R2X36_RS19045 (R2X36_19045) mutT 4110187..4110591 (-) 405 WP_005332118.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45535.60 Da        Isoelectric Point: 10.1464

>NTDB_id=894230 R2X36_RS19020 WP_043133310.1 4106320..4107561(+) (pilC) [Aeromonas media strain QST31]
MATLAQKRNTPKKVFSFRWHGFNRKGQKVSGEFQADSINTVKAELRKQGVNVTKVSKQGQGLFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIATDVETGTPLSEALRRHPRHFDALYCDLVDAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPVFTRFVIGISRFMQAWWYIIFGGTA
LAIFLYVRAWRKSQKVRDNTDRFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAILAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=894230 R2X36_RS19020 WP_043133310.1 4106320..4107561(+) (pilC) [Aeromonas media strain QST31]
ATGGCAACATTAGCGCAAAAACGTAACACACCTAAAAAGGTCTTCTCCTTCCGCTGGCATGGATTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGTTCCAGGCCGACAGCATCAACACCGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
AGGTCAGCAAGCAGGGCCAGGGCCTGTTTTCCAAGGGGGGTGCTCGGATCAAGCCGATGGACATCGCCGTCATCTCCCGT
CAGATCACCACCATGCTCTCGGCCGGTGTGCCGCTGGTGCAAAGCTTGCAGATCATCGCCCGCGGTCATGAGAAGGCAGC
AGTACGCGAACTCATCGGCCAGATCGCCACCGATGTGGAAACCGGCACCCCGCTGTCAGAGGCGCTGCGCCGCCACCCCC
GTCACTTCGATGCGCTCTACTGCGATCTGGTAGACGCAGGGGAGCAGTCCGGCGCGCTGGAAACCATCTACGACCGGATT
GCCACATACCGCGAGAAGAGTGAGGCGCTGAAGTCCAAGATCAAGAAGGCAATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATTGTGACCTCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGAGATCTTCAAGAGCTTCGGGGCAGAGC
TGCCAGTCTTCACCCGATTCGTCATCGGTATCTCCCGCTTCATGCAAGCTTGGTGGTATATCATCTTTGGTGGCACAGCC
TTGGCCATCTTCCTCTATGTGCGCGCCTGGCGAAAATCCCAGAAGGTACGGGACAACACCGACAGATTCATCCTCACCAT
TCCGGTCGTGGGCAACATATTGCACAAGGCGGCCATGGCCCGTTTCGCCCGTACCCTCTCCACCACCTTCTCCGCCGGGA
TACCTCTGGTGGATGCTCTGGTATCAGCGGCCGGCGCCTCTGGCAACTATGTCTATCGCACGGCCATCCTGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGTACCGTGGATCTCTTCCCAGACATGGTGATCCAGATGGT
GATGATTGGTGAAGAGTCAGGCGCCATCGATGACATGCTCTCCAAGGTTGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTACTCGGGGTGCTGGTCGGTGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.818

95.884

0.545
  pilC Legionella pneumophila strain ERS1305867

53.086

98.063

0.521
  pilC Acinetobacter baumannii D1279779

51.122

97.094

0.496
  pilC Acinetobacter baylyi ADP1

50.63

96.126

0.487
  pilC Vibrio cholerae strain A1552

48

96.852

0.465
  pilC Vibrio campbellii strain DS40M4

46.482

96.368

0.448
  pilG Neisseria gonorrhoeae MS11

40.05

97.337

0.39
  pilG Neisseria meningitidis 44/76-A

39.801

97.337

0.387
  pilC Thermus thermophilus HB27

39

96.852

0.378