Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   RMP65_RS00765 Genome accession   NZ_CP135089
Coordinates   119475..120425 (+) Length   316 a.a.
NCBI ID   WP_074391327.1    Uniprot ID   -
Organism   Streptococcus suis strain ID34567     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114475..125425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP65_RS00755 (RMP65_00755) - 118037..118411 (+) 375 WP_024385120.1 DUF1033 family protein -
  RMP65_RS00760 (RMP65_00760) - 118439..119389 (-) 951 WP_074391326.1 S66 peptidase family protein -
  RMP65_RS00765 (RMP65_00765) comYA 119475..120425 (+) 951 WP_074391327.1 competence type IV pilus ATPase ComGA Machinery gene
  RMP65_RS00770 (RMP65_00770) comYB 120337..121374 (+) 1038 WP_269472402.1 competence type IV pilus assembly protein ComGB Machinery gene
  RMP65_RS00775 (RMP65_00775) comYC 121376..121657 (+) 282 WP_074391328.1 competence type IV pilus major pilin ComGC Machinery gene
  RMP65_RS00780 (RMP65_00780) comGD 121638..122045 (+) 408 WP_074391329.1 competence type IV pilus minor pilin ComGD -
  RMP65_RS00785 (RMP65_00785) comYE 122017..122310 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  RMP65_RS00790 (RMP65_00790) comGF/cglF 122297..122731 (+) 435 WP_044762030.1 competence type IV pilus minor pilin ComGF Machinery gene
  RMP65_RS00795 (RMP65_00795) comGG 122709..123122 (+) 414 WP_074391330.1 competence type IV pilus minor pilin ComGG -
  RMP65_RS00800 (RMP65_00800) comYH 123172..124125 (+) 954 WP_024414316.1 class I SAM-dependent methyltransferase Machinery gene
  RMP65_RS00805 (RMP65_00805) - 124175..125362 (+) 1188 WP_044680792.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35399.21 Da        Isoelectric Point: 5.6938

>NTDB_id=884910 RMP65_RS00765 WP_074391327.1 119475..120425(+) (comYA) [Streptococcus suis strain ID34567]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIAFGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=884910 RMP65_RS00765 WP_074391327.1 119475..120425(+) (comYA) [Streptococcus suis strain ID34567]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCAGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGGCTATCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACGTGGCTGAAGAGGAAGTGACAGCCA
TTATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGTAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGACCAGACTTGCTCATCATCGGAGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGAGTCTAT
GCCCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCTTTGGATCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.064

98.734

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.064

98.734

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.064

98.734

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.064

98.734

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.064

98.734

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361