Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   RIN70_RS10250 Genome accession   NZ_CP134147
Coordinates   2113064..2113822 (-) Length   252 a.a.
NCBI ID   WP_003009229.1    Uniprot ID   V8B9D8
Organism   Streptococcus parasanguinis strain 30.8.10     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2108064..2118822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIN70_RS10230 (RIN70_10230) - 2108518..2110143 (+) 1626 WP_049486042.1 ATP-binding cassette domain-containing protein -
  RIN70_RS10235 (RIN70_10235) - 2110193..2112769 (+) 2577 WP_070664934.1 YfhO family protein -
  RIN70_RS10250 (RIN70_10250) comE/comE2 2113064..2113822 (-) 759 WP_003009229.1 response regulator transcription factor Regulator
  RIN70_RS10255 (RIN70_10255) - 2113819..2115159 (-) 1341 WP_049473259.1 GHKL domain-containing protein -
  RIN70_RS10265 (RIN70_10265) rlmH 2115618..2116097 (-) 480 WP_272144733.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RIN70_RS10270 (RIN70_10270) htrA 2116302..2117483 (+) 1182 WP_272144731.1 S1C family serine protease Regulator
  RIN70_RS10275 (RIN70_10275) spo0J 2117555..2118316 (+) 762 WP_070594308.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29548.05 Da        Isoelectric Point: 5.4835

>NTDB_id=878890 RIN70_RS10250 WP_003009229.1 2113064..2113822(-) (comE/comE2) [Streptococcus parasanguinis strain 30.8.10]
MKIFLLEDELSQQIRVEKHIAEIAKELEIKLEVISTGKISEFENYIQHSDIHQLYFLDIHIQDNEYCGLEIAQKIREANP
YAIIVFITTKSEFASITYRYKVSALDFIDKNLNEDLFRLKIKECIEYLTTIQIGNDDLTDYFEYDFKDKKIKIPFKDILY
IETVGSAYKLNLVGKNFQKEIAGSLSDVLEKDVEERYFSPHQSFIVNRSMIIGMDKKKKQLLLKEGYSCPISRSNIKRAK
KLIEEQNLEFSA

Nucleotide


Download         Length: 759 bp        

>NTDB_id=878890 RIN70_RS10250 WP_003009229.1 2113064..2113822(-) (comE/comE2) [Streptococcus parasanguinis strain 30.8.10]
ATGAAGATTTTTTTATTAGAAGATGAGCTCTCTCAACAGATACGGGTAGAAAAACATATTGCAGAAATTGCTAAGGAATT
AGAAATTAAACTTGAAGTGATTTCTACCGGTAAAATTTCGGAATTTGAAAATTATATCCAGCATTCGGATATCCACCAAT
TATATTTTCTAGATATTCATATCCAAGACAATGAGTATTGTGGGCTGGAAATTGCTCAAAAAATACGAGAAGCAAATCCT
TATGCCATTATTGTTTTTATTACTACAAAATCAGAATTTGCTTCGATTACCTATCGTTATAAAGTATCTGCCTTAGATTT
TATTGATAAAAATTTGAATGAAGATTTATTTAGATTAAAAATTAAGGAGTGTATTGAGTATCTAACGACTATTCAAATTG
GAAATGATGATTTGACAGATTATTTTGAGTATGACTTTAAAGATAAAAAGATAAAAATTCCATTTAAGGATATTCTTTAT
ATTGAAACTGTTGGTTCGGCTTATAAATTAAACTTAGTTGGGAAAAATTTTCAAAAAGAAATTGCGGGAAGTTTATCAGA
TGTCTTGGAGAAAGATGTGGAGGAGAGATATTTCAGTCCCCATCAATCTTTTATCGTGAATAGAAGTATGATCATTGGAA
TGGATAAGAAAAAGAAACAGCTACTGTTGAAAGAAGGCTATTCTTGTCCAATCTCAAGAAGCAATATCAAACGTGCCAAA
AAATTAATTGAAGAGCAAAATTTAGAATTTAGTGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(29-120)

LytTr DNA-binding domain (LytTR)

(149-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB V8B9D8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

49.194

98.413

0.484
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

49.194

98.413

0.484
  comE Streptococcus pneumoniae Rx1

47.177

98.413

0.464
  comE Streptococcus pneumoniae D39

47.177

98.413

0.464
  comE Streptococcus pneumoniae R6

47.177

98.413

0.464
  comE Streptococcus pneumoniae TIGR4

47.177

98.413

0.464
  comE Streptococcus mitis NCTC 12261

47.177

98.413

0.464
  comE Streptococcus mitis SK321

47.177

98.413

0.464
  comE Streptococcus infantis strain Atu-4

45.968

98.413

0.452
  comE/blpR Streptococcus mutans UA159

38.866

98.016

0.381