Detailed information NTG0878891

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: RIN70_RS10270
• Genome accession: NZ_CP134147
• Coordinates: 2116302..2117483 (+)
• Length: 393 a.a.
• NCBI ID: WP_272144731.1
• Uniprot ID: -
• Organism: Streptococcus parasanguinis strain 30.8.10
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2111302..2122483

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIN70_RS10250 (RIN70_10250)	comE/comE2	2113064..2113822 (-)	759	WP_003009229.1	response regulator transcription factor	Regulator
RIN70_RS10255 (RIN70_10255)	-	2113819..2115159 (-)	1341	WP_049473259.1	GHKL domain-containing protein	-
RIN70_RS10265 (RIN70_10265)	rlmH	2115618..2116097 (-)	480	WP_272144733.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
RIN70_RS10270 (RIN70_10270)	htrA	2116302..2117483 (+)	1182	WP_272144731.1	S1C family serine protease	Regulator
RIN70_RS10275 (RIN70_10275)	spo0J	2117555..2118316 (+)	762	WP_070594308.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 41704.81 Da
• Isoelectric Point: 5.7871

>NTDB_id=878891 RIN70_RS10270 WP_272144731.1 2116302..2117483(+) (htrA) [Streptococcus parasanguinis strain 30.8.10]
MKSSSNLLKKVGNIALIFVVGFLGGILGTFLTLQTSHSSTSNTESKQVHSTTVKTAYKNTTSTSEAVDKVKNAVVSVITY
SDSSNQGLFEKEENSDSQISSEGSGVIYKKEGKYAYLVTNTHVINGAKKVDILLADGNKVPGEVVGSDVYSDIAVVRISA
DKAKAVAEFGDSNQLTVGETAIAIGSPLGTDYANSVTQGIISSQGRNVKLKADNGQNISTRALQTDAAINPGNSGGPLIN
IQGQIIGITSSKISNNGQTSVEGMGFAIPANDVVNIIKQLEEKGKVVRPALGIQMMDLSNLSTSDLSQLKLPEKISGGVL
VRSTLENMPASDKLQRYDVITKIDDTDIESTADLQSALYSHQINDTIKVTFYRDGKQQTTSIKLTKSTEDLSD

Nucleotide

• Length: 1182 bp

>NTDB_id=878891 RIN70_RS10270 WP_272144731.1 2116302..2117483(+) (htrA) [Streptococcus parasanguinis strain 30.8.10]
ATGAAATCTTCATCTAATTTACTGAAAAAAGTTGGAAACATAGCCCTCATTTTTGTTGTAGGTTTTCTAGGTGGGATTCT
TGGAACCTTTTTAACCTTACAAACCTCTCATTCTTCTACTTCAAATACTGAAAGTAAGCAAGTACACTCAACCACTGTTA
AAACAGCTTATAAAAATACAACCTCAACTAGTGAGGCCGTAGACAAGGTGAAAAATGCTGTGGTTTCTGTGATTACTTAT
TCTGATTCTTCGAATCAAGGGTTATTTGAAAAAGAAGAAAACTCTGACTCACAAATTTCTAGTGAAGGTTCTGGGGTCAT
TTATAAAAAAGAAGGAAAATATGCCTACCTTGTTACCAACACCCATGTAATCAATGGTGCTAAAAAAGTAGACATTCTTT
TAGCAGATGGTAATAAAGTCCCCGGAGAAGTAGTTGGGTCAGATGTCTATTCTGATATTGCAGTCGTTCGCATCAGTGCG
GATAAAGCAAAGGCAGTAGCTGAATTCGGAGATTCAAACCAATTAACGGTTGGTGAGACTGCGATTGCGATCGGTAGCCC
TCTTGGAACAGATTATGCTAATTCTGTTACCCAAGGAATTATTTCCAGCCAAGGCCGCAATGTGAAATTGAAAGCCGATA
ATGGACAAAATATCTCTACACGCGCCTTACAAACAGACGCAGCCATCAACCCAGGAAACTCTGGAGGTCCATTAATCAAT
ATTCAAGGACAAATCATCGGGATTACCTCAAGTAAAATTTCAAATAACGGACAAACTTCAGTAGAAGGAATGGGATTTGC
AATTCCTGCAAATGATGTTGTCAATATTATCAAGCAGCTAGAAGAAAAAGGAAAAGTAGTTCGACCAGCTCTTGGAATCC
AAATGATGGATTTATCCAACCTTTCAACTTCTGATTTAAGCCAATTAAAACTTCCTGAAAAAATCTCTGGAGGAGTACTA
GTTCGTTCAACACTTGAAAATATGCCTGCTTCAGATAAATTGCAACGTTATGATGTCATCACAAAGATCGATGATACAGA
TATCGAGTCAACTGCAGATTTACAATCCGCCCTCTATTCTCACCAAATCAATGATACAATCAAGGTCACATTCTATCGTG
ATGGAAAACAACAAACAACTTCTATCAAGTTGACAAAATCAACTGAGGATCTGAGCGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (289-384)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	67.839	100	0.687
htrA	Streptococcus mitis NCTC 12261	63.104	100	0.631
htrA	Streptococcus pneumoniae Rx1	63.104	100	0.631
htrA	Streptococcus pneumoniae D39	63.104	100	0.631
htrA	Streptococcus pneumoniae R6	63.104	100	0.631
htrA	Streptococcus pneumoniae TIGR4	63.104	100	0.631
htrA	Streptococcus mutans UA159	53.766	97.964	0.527