Detailed information NTG0878844

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: RIN70_RS01320
• Genome accession: NZ_CP134147
• Coordinates: 228363..229097 (+)
• Length: 244 a.a.
• NCBI ID: WP_118228517.1
• Uniprot ID: -
• Organism: Streptococcus parasanguinis strain 30.8.10
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 223363..234097

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIN70_RS01300 (RIN70_01300)	-	224149..225003 (+)	855	WP_037585172.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
RIN70_RS01305 (RIN70_01305)	-	225102..225395 (+)	294	WP_031572673.1	hypothetical protein	-
RIN70_RS01310 (RIN70_01310)	groES	225525..225806 (+)	282	WP_024055367.1	co-chaperone GroES	-
RIN70_RS01315 (RIN70_01315)	groL	225828..227453 (+)	1626	WP_070590330.1	chaperonin GroEL	-
RIN70_RS01320 (RIN70_01320)	comE/blpR	228363..229097 (+)	735	WP_118228517.1	response regulator transcription factor	Regulator
RIN70_RS01325 (RIN70_01325)	-	229128..230414 (+)	1287	WP_241672902.1	sensor histidine kinase	-
RIN70_RS01330 (RIN70_01330)	-	230704..231384 (+)	681	WP_272144446.1	ABC transporter ATP-binding protein	-
RIN70_RS01335 (RIN70_01335)	-	231381..232088 (+)	708	WP_003017225.1	hypothetical protein	-
RIN70_RS01340 (RIN70_01340)	-	232139..233248 (-)	1110	WP_118095970.1	SPFH domain-containing protein	-
RIN70_RS01345 (RIN70_01345)	-	233260..233817 (-)	558	WP_272144443.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28203.50 Da
• Isoelectric Point: 6.6114

>NTDB_id=878844 RIN70_RS01320 WP_118228517.1 228363..229097(+) (comE/blpR) [Streptococcus parasanguinis strain 30.8.10]
MLKIFVLEDEWIQQSRIEAVLQDLIRQKFLQCKAPEVFGKSSQLLDAITERGAHHLFFLDIEIKGEEKKGLEIAKEIRKK
DPHATIVFVTTHSEFMPITFQYKVAALDFIDKTLSEEEFKERISSAIDYTLEQAGTTIAQDAFTFESAMARVQVPFNKIL
YVETSPAIHKVILHTQEERLEFYASIADIEKADPRLYRCHRSFVVNPQNITKIDKEAKKAFFENGDNCLISRTKYRGLLE
ALKK

Nucleotide

• Length: 735 bp

>NTDB_id=878844 RIN70_RS01320 WP_118228517.1 228363..229097(+) (comE/blpR) [Streptococcus parasanguinis strain 30.8.10]
TTGTTGAAGATTTTTGTGTTAGAAGATGAATGGATCCAACAATCGCGTATCGAAGCGGTCTTGCAGGATCTCATCCGTCA
AAAATTCTTGCAATGCAAAGCGCCAGAAGTGTTTGGGAAGTCAAGCCAGTTGCTGGATGCTATCACAGAGAGAGGCGCCC
ATCACCTATTCTTTTTAGATATCGAGATTAAAGGTGAGGAGAAAAAAGGTCTGGAGATCGCAAAAGAGATTCGTAAGAAA
GACCCCCATGCGACCATTGTCTTTGTCACCACTCACTCTGAATTCATGCCCATTACCTTTCAGTACAAAGTAGCTGCCTT
GGATTTTATCGATAAAACGCTGAGTGAGGAAGAGTTCAAAGAGAGAATCAGCTCAGCCATCGACTATACCTTGGAGCAAG
CTGGGACCACGATTGCGCAAGATGCCTTTACGTTTGAGAGTGCGATGGCGCGTGTACAAGTTCCTTTTAATAAGATTTTG
TATGTTGAAACGTCTCCAGCCATTCACAAGGTCATTTTACACACCCAGGAAGAGCGCTTGGAATTTTACGCTAGTATTGC
CGATATCGAAAAAGCAGATCCCCGCTTGTATCGGTGCCACCGCTCCTTTGTGGTGAATCCGCAAAATATTACGAAGATTG
ATAAAGAAGCCAAGAAAGCTTTTTTTGAAAATGGAGACAATTGCTTGATCTCACGGACCAAGTATAGAGGCTTACTGGAA
GCTTTGAAAAAATAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.812	97.951	0.537
comE/comE1	Streptococcus equinus JB1	45.267	99.59	0.451
comE/comE2	Streptococcus gordonii strain NCTC7865	40.244	100	0.406
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.244	100	0.406
comE/comE2	Streptococcus equinus JB1	38.462	100	0.389
comE	Streptococcus pneumoniae TIGR4	36.4	100	0.373
comE	Streptococcus mitis SK321	36.4	100	0.373
comE	Streptococcus mitis NCTC 12261	36.4	100	0.373
comE	Streptococcus infantis strain Atu-4	36.4	100	0.373
comE	Streptococcus pneumoniae Rx1	36.4	100	0.373
comE	Streptococcus pneumoniae D39	36.4	100	0.373
comE	Streptococcus pneumoniae R6	36.4	100	0.373