Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q2F48_RS02230 Genome accession   NZ_CP130164
Coordinates   452125..453366 (-) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain WZDHY22015     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 447125..458366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2F48_RS02200 (Q2F48_02200) - 447919..449103 (+) 1185 WP_216987869.1 tetratricopeptide repeat protein -
  Q2F48_RS02205 (Q2F48_02205) mutT 449112..449516 (+) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  Q2F48_RS02210 (Q2F48_02210) yacG 449574..449768 (-) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  Q2F48_RS02215 (Q2F48_02215) zapD 449779..450501 (-) 723 WP_279961679.1 cell division protein ZapD -
  Q2F48_RS02220 (Q2F48_02220) coaE 450539..451153 (-) 615 WP_109111851.1 dephospho-CoA kinase -
  Q2F48_RS02225 (Q2F48_02225) pilD 451172..452047 (-) 876 WP_119197036.1 A24 family peptidase Machinery gene
  Q2F48_RS02230 (Q2F48_02230) pilC 452125..453366 (-) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  Q2F48_RS02235 (Q2F48_02235) pilB 453494..455200 (-) 1707 WP_041213997.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  Q2F48_RS02240 (Q2F48_02240) - 455208..455582 (-) 375 WP_103261553.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  Q2F48_RS02245 (Q2F48_02245) nadC 455893..456756 (-) 864 WP_052814467.1 carboxylating nicotinate-nucleotide diphosphorylase -
  Q2F48_RS02250 (Q2F48_02250) - 456760..457230 (-) 471 WP_104452204.1 retropepsin-like aspartic protease -
  Q2F48_RS02255 (Q2F48_02255) ampD 457359..457931 (+) 573 WP_103244159.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=857418 Q2F48_RS02230 WP_010675822.1 452125..453366(-) (pilC) [Aeromonas caviae strain WZDHY22015]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=857418 Q2F48_RS02230 WP_010675822.1 452125..453366(-) (pilC) [Aeromonas caviae strain WZDHY22015]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCCCGCGGCCACGAGAAAGCGGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAATTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCACGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTAGTAGCC
ATGTACCTCCCCATTTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375