Detailed information NTG0853760

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U67_RS08180
• Genome accession: NZ_CP145865
• Coordinates: 1793135..1793875 (+)
• Length: 246 a.a.
• NCBI ID: WP_014634987.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS8
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1788135..1798875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U67_RS08155 (V6U67_08165)	gla	1788204..1789067 (-)	864	WP_037611925.1	aquaglyceroporin Gla	-
V6U67_RS08160 (V6U67_08170)	-	1789188..1791455 (+)	2268	WP_037611926.1	Xaa-Pro dipeptidyl-peptidase	-
V6U67_RS08165 (V6U67_08175)	-	1791655..1791951 (-)	297	WP_014634985.1	bacteriocin immunity protein	-
V6U67_RS08170 (V6U67_08180)	-	1792319..1792711 (-)	393	WP_003094909.1	hypothetical protein	-
V6U67_RS08175 (V6U67_08185)	-	1792747..1792881 (-)	135	Protein_1570	Blp family class II bacteriocin	-
V6U67_RS08180 (V6U67_08190)	comE/blpR	1793135..1793875 (+)	741	WP_014634987.1	response regulator transcription factor	Regulator
V6U67_RS08185 (V6U67_08195)	comD/comD3	1794457..1795206 (+)	750	WP_014634988.1	sensor histidine kinase	Regulator
V6U67_RS08190 (V6U67_08200)	-	1795293..1795694 (-)	402	WP_014634989.1	hypothetical protein	-
V6U67_RS08195 (V6U67_08205)	-	1796669..1796899 (-)	231	WP_037611928.1	bacteriocin class II family protein	-
V6U67_RS08200 (V6U67_08210)	-	1797060..1798805 (-)	1746	WP_037611929.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28677.27 Da
• Isoelectric Point: 8.4293

>NTDB_id=853760 V6U67_RS08180 WP_014634987.1 1793135..1793875(+) (comE/blpR) [Streptococcus salivarius strain KSS8]
MDIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIEIKGEKLKGLDIAKIIREKN
PYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIRIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
KRRNLQ

Nucleotide

• Length: 741 bp

>NTDB_id=853760 V6U67_RS08180 WP_014634987.1 1793135..1793875(+) (comE/blpR) [Streptococcus salivarius strain KSS8]
TTGGATATATATATCTTAGAGGACAATCTCATTCAACAAGGACGACTGGAGATGGTATTGTCTCAAGAGTTAAAAAAATA
CAATAAAGACTTATCTATTGTACACACCTTTGATAAGCCTCAGCAATTTATAGAAGCGATTGATTCAACAACTTCTAACC
AGCTCTTTTTTCTTGATATCGAAATTAAGGGAGAAAAATTAAAAGGGCTCGATATTGCTAAAATCATTAGGGAAAAAAAT
CCCTACGCTACTATTATCTTTGTCACTACCCACTCAGAGTTTATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATTGATAAAAGTCTCTCTGAAATAGAATTTAGGAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GAATAGAGAATGACGAGATTTTTGATTTTCAAACACAACATACAGCTATTCGCATACCTTTAAACCAAGTTATCTATATT
GAAACTTCTCCGCAAAAGCATTATGTGATACTCCATGGTACAAACAATCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCATCGTTCGTATCTCATTAACCCTAACAACATTATAAGAATCAACAAAT
TAAAACGTGAAGTCGAAATGACTGATGGTAGTATCTGTCCTTTTTCACGTACCAAAGCTAAAATGCTGATGGATACTTTT
AAAAGAAGGAACCTTCAATGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (150-239)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	43.59	95.122	0.415
comE/comE2	Streptococcus equinus JB1	39.241	96.341	0.378
comE/comE2	Streptococcus gordonii strain NCTC7865	37.2	100	0.378
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.2	100	0.378
comE/comE1	Streptococcus equinus JB1	38.655	96.748	0.374
comE	Streptococcus pneumoniae TIGR4	35.6	100	0.362
comE	Streptococcus mitis SK321	35.6	100	0.362
comE	Streptococcus mitis NCTC 12261	35.6	100	0.362
comE	Streptococcus infantis strain Atu-4	35.6	100	0.362
comE	Streptococcus pneumoniae Rx1	35.6	100	0.362
comE	Streptococcus pneumoniae D39	35.6	100	0.362
comE	Streptococcus pneumoniae R6	35.6	100	0.362