Detailed information NTG0853585

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U66_RS02480
• Genome accession: NZ_CP145864
• Coordinates: 474731..475462 (+)
• Length: 243 a.a.
• NCBI ID: WP_070437583.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 469731..480462

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS02465 (V6U66_02470)	-	471177..472085 (+)	909	WP_073685810.1	thiopeptide-type bacteriocin biosynthesis protein	-
V6U66_RS02470 (V6U66_02475)	-	472086..472898 (+)	813	WP_070437591.1	SagB/ThcOx family dehydrogenase	-
V6U66_RS02475 (V6U66_02480)	-	472916..473662 (+)	747	WP_073685811.1	hypothetical protein	-
V6U66_RS02480 (V6U66_02485)	comE/blpR	474731..475462 (+)	732	WP_070437583.1	response regulator transcription factor	Regulator
V6U66_RS02485 (V6U66_02490)	-	475499..476812 (+)	1314	WP_070437580.1	sensor histidine kinase	-
V6U66_RS02490 (V6U66_02495)	-	477500..478393 (+)	894	WP_410534548.1	ribonuclease D	-
V6U66_RS02495 (V6U66_02500)	-	478707..479453 (+)	747	WP_149561043.1	DUF6994 family protein	-
V6U66_RS02500 (V6U66_02505)	-	479501..480007 (+)	507	WP_410534549.1	NUDIX hydrolase	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28359.46 Da
• Isoelectric Point: 5.6753

>NTDB_id=853585 V6U66_RS02480 WP_070437583.1 474731..475462(+) (comE/blpR) [Streptococcus salivarius strain KSS7]
MINIFVLEDEILQQSRIENTITEVLTKHSWKCKGPEIFGKPSQMLEAIVERGSHQLFFLDIEIRGEEKKGLDIARQIREQ
DPHATIVFVTTHSEFMPITFKYKVAALDFVDKALGNEQFTYRIESIIEYAMEKEGQAVSQDAFKFETSLAQVQVPFNKVL
YFETSPTVHKVILHTTDERLEFYASISEVERADERLYRCHKSFVVNPENIEKIDKEQRIVYFDGDQNCLISRSKMKGLKE
RIK

Nucleotide

• Length: 732 bp

>NTDB_id=853585 V6U66_RS02480 WP_070437583.1 474731..475462(+) (comE/blpR) [Streptococcus salivarius strain KSS7]
ATGATTAACATCTTTGTTCTAGAAGACGAAATTTTACAGCAATCTCGTATTGAAAATACGATAACAGAGGTTCTAACAAA
GCATTCTTGGAAATGTAAGGGACCTGAGATTTTTGGGAAACCCTCTCAAATGCTAGAAGCAATAGTTGAACGTGGTTCCC
ATCAACTATTCTTTCTAGATATTGAAATAAGGGGAGAAGAGAAAAAAGGATTAGATATTGCTAGACAAATACGTGAACAA
GATCCACATGCCACAATCGTATTTGTAACGACGCATTCAGAGTTTATGCCTATAACTTTTAAATACAAAGTAGCTGCTTT
AGACTTTGTTGATAAAGCCCTAGGAAACGAACAATTTACTTATCGGATTGAATCTATTATCGAGTATGCCATGGAAAAAG
AAGGACAGGCAGTCTCTCAAGATGCCTTTAAGTTTGAAACATCTTTGGCACAAGTTCAGGTTCCTTTTAATAAAGTATTG
TATTTTGAGACTTCCCCAACGGTTCACAAAGTAATTCTACATACGACAGATGAACGTCTTGAGTTTTATGCAAGTATATC
GGAAGTTGAAAGGGCAGATGAACGACTATATCGTTGTCATAAGTCTTTTGTTGTCAATCCAGAAAATATTGAAAAAATAG
ATAAAGAACAAAGAATTGTTTATTTTGATGGGGACCAAAATTGTTTAATCTCTCGTTCAAAAATGAAGGGCTTGAAAGAA
CGGATTAAATAG

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.51	100	0.56
comE/comE1	Streptococcus equinus JB1	46.218	97.942	0.453
comE/comE2	Streptococcus equinus JB1	40.083	99.588	0.399
comE	Streptococcus mitis SK321	38.115	100	0.383
comE	Streptococcus pneumoniae R6	38.115	100	0.383
comE	Streptococcus pneumoniae TIGR4	38.115	100	0.383
comE	Streptococcus mitis NCTC 12261	38.115	100	0.383
comE	Streptococcus pneumoniae Rx1	38.115	100	0.383
comE	Streptococcus pneumoniae D39	38.115	100	0.383
comE	Streptococcus infantis strain Atu-4	37.652	100	0.383
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.247	100	0.379
comE/comE2	Streptococcus gordonii strain NCTC7865	37.247	100	0.379