Detailed information NTG0852976

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6T01_RS08495
• Genome accession: NZ_CP145856
• Coordinates: 1842399..1843139 (+)
• Length: 246 a.a.
• NCBI ID: WP_014634987.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS1
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1837399..1848139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6T01_RS08470 (V6T01_08445)	-	1837400..1839667 (+)	2268	WP_410541326.1	Xaa-Pro dipeptidyl-peptidase	-
V6T01_RS08475 (V6T01_08450)	-	1839864..1840808 (+)	945	WP_410541175.1	IS30 family transposase	-
V6T01_RS08480 (V6T01_08455)	-	1840918..1841214 (-)	297	WP_014634985.1	bacteriocin immunity protein	-
V6T01_RS08485 (V6T01_08460)	-	1841583..1841975 (-)	393	WP_003094909.1	hypothetical protein	-
V6T01_RS08490 (V6T01_08465)	-	1842011..1842145 (-)	135	Protein_1633	Blp family class II bacteriocin	-
V6T01_RS08495 (V6T01_08470)	comE/blpR	1842399..1843139 (+)	741	WP_014634987.1	response regulator transcription factor	Regulator
V6T01_RS08500 (V6T01_08475)	comD/comD3	1843721..1844470 (+)	750	WP_014634988.1	sensor histidine kinase	Regulator
V6T01_RS08505 (V6T01_08480)	-	1844557..1844958 (-)	402	WP_014634989.1	hypothetical protein	-
V6T01_RS08510 (V6T01_08485)	-	1845933..1846163 (-)	231	WP_118189325.1	Blp family class II bacteriocin	-
V6T01_RS08515 (V6T01_08490)	-	1846323..1848071 (-)	1749	WP_410541325.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28677.27 Da
• Isoelectric Point: 8.4293

>NTDB_id=852976 V6T01_RS08495 WP_014634987.1 1842399..1843139(+) (comE/blpR) [Streptococcus salivarius strain KSS1]
MDIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIEIKGEKLKGLDIAKIIREKN
PYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIRIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
KRRNLQ

Nucleotide

• Length: 741 bp

>NTDB_id=852976 V6T01_RS08495 WP_014634987.1 1842399..1843139(+) (comE/blpR) [Streptococcus salivarius strain KSS1]
TTGGATATATATATCTTAGAGGACAATCTCATTCAACAAGGACGACTGGAGATGGTATTGTCTCAAGAGTTAAAAAAATA
CAATAAAGACTTATCTATTGTACACACCTTTGATAAGCCTCAGCAATTTATAGAAGCGATTGATTCAACAACTTCTAACC
AGCTCTTTTTTCTTGATATCGAAATTAAGGGAGAAAAATTAAAAGGGCTCGATATTGCTAAAATCATTAGGGAAAAAAAT
CCCTACGCTACTATTATCTTTGTCACTACCCACTCAGAGTTTATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATTGATAAAAGTCTCTCTGAAATAGAATTTAGGAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GAATAGAGAATGACGAGATTTTTGATTTTCAAACACAACATACAGCTATTCGCATACCTTTAAACCAAGTTATCTATATT
GAAACTTCTCCGCAAAAGCATTATGTGATACTCCATGGTACAAACAATCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCATCGTTCGTATCTCATTAACCCTAACAACATTATAAGAATCAACAAAT
TAAAACGTGAAGTCGAAATGACTGATGGTAGTATCTGTCCTTTTTCACGTACCAAAGCTAAAATGCTGATGGATACTTTT
AAAAGAAGGAACCTTCAATGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (150-239)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	43.59	95.122	0.415
comE/comE2	Streptococcus equinus JB1	39.241	96.341	0.378
comE/comE2	Streptococcus gordonii strain NCTC7865	37.2	100	0.378
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.2	100	0.378
comE/comE1	Streptococcus equinus JB1	38.655	96.748	0.374
comE	Streptococcus pneumoniae TIGR4	35.6	100	0.362
comE	Streptococcus mitis SK321	35.6	100	0.362
comE	Streptococcus mitis NCTC 12261	35.6	100	0.362
comE	Streptococcus infantis strain Atu-4	35.6	100	0.362
comE	Streptococcus pneumoniae Rx1	35.6	100	0.362
comE	Streptococcus pneumoniae D39	35.6	100	0.362
comE	Streptococcus pneumoniae R6	35.6	100	0.362