Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   VKP56_RS08545 Genome accession   NZ_CP142350
Coordinates   1713616..1714887 (-) Length   423 a.a.
NCBI ID   WP_326657022.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1445     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1708616..1719887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS08520 (VKP56_08520) - 1710585..1710890 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  VKP56_RS08525 (VKP56_08525) ruvX 1710902..1711321 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  VKP56_RS08530 (VKP56_08530) - 1711318..1711587 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  VKP56_RS08535 (VKP56_08535) spx 1711702..1712100 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  VKP56_RS08540 (VKP56_08540) recA 1712391..1713527 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  VKP56_RS08545 (VKP56_08545) cinA 1713616..1714887 (-) 1272 WP_326657022.1 competence/damage-inducible protein A Machinery gene
  VKP56_RS08550 (VKP56_08550) - 1714956..1715516 (-) 561 WP_023079151.1 DNA-3-methyladenine glycosylase I -
  VKP56_RS08555 (VKP56_08555) ruvA 1715526..1716122 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  VKP56_RS08560 (VKP56_08560) - 1716124..1717344 (-) 1221 WP_136094270.1 MDR family MFS transporter -
  VKP56_RS08565 (VKP56_08565) hexB 1717355..1719337 (-) 1983 WP_326657028.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45961.65 Da        Isoelectric Point: 4.8210

>NTDB_id=840166 VKP56_RS08545 WP_326657022.1 1713616..1714887(-) (cinA) [Streptococcus pyogenes strain SS1445]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQQLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNQELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKALISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=840166 VKP56_RS08545 WP_326657022.1 1713616..1714887(-) (cinA) [Streptococcus pyogenes strain SS1445]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTAATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGCAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATCAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACAGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGCTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterProScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.504

100

0.695
  cinA Streptococcus mitis SK321

69.544

98.582

0.686
  cinA Streptococcus mitis NCTC 12261

69.065

98.582

0.681
  cinA Streptococcus pneumoniae TIGR4

68.106

98.582

0.671
  cinA Streptococcus pneumoniae R36A

68.106

98.582

0.671
  cinA Streptococcus pneumoniae Rx1

68.106

98.582

0.671
  cinA Streptococcus pneumoniae R6

68.106

98.582

0.671
  cinA Streptococcus pneumoniae D39

67.866

98.582

0.669
  cinA Streptococcus suis isolate S10

52.644

98.345

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461