Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   VKP56_RS08555 Genome accession   NZ_CP142350
Coordinates   1715526..1716122 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes strain SS1445     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1710526..1721122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS08520 (VKP56_08520) - 1710585..1710890 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  VKP56_RS08525 (VKP56_08525) ruvX 1710902..1711321 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  VKP56_RS08530 (VKP56_08530) - 1711318..1711587 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  VKP56_RS08535 (VKP56_08535) spx 1711702..1712100 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  VKP56_RS08540 (VKP56_08540) recA 1712391..1713527 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  VKP56_RS08545 (VKP56_08545) cinA 1713616..1714887 (-) 1272 WP_326657022.1 competence/damage-inducible protein A Machinery gene
  VKP56_RS08550 (VKP56_08550) - 1714956..1715516 (-) 561 WP_023079151.1 DNA-3-methyladenine glycosylase I -
  VKP56_RS08555 (VKP56_08555) ruvA 1715526..1716122 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  VKP56_RS08560 (VKP56_08560) - 1716124..1717344 (-) 1221 WP_136094270.1 MDR family MFS transporter -
  VKP56_RS08565 (VKP56_08565) hexB 1717355..1719337 (-) 1983 WP_326657028.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=840167 VKP56_RS08555 WP_002991359.1 1715526..1716122(-) (ruvA) [Streptococcus pyogenes strain SS1445]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=840167 VKP56_RS08555 WP_002991359.1 1715526..1716122(-) (ruvA) [Streptococcus pyogenes strain SS1445]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424