Detailed information NTG0082903

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: H7677_RS06080
• Genome accession: NZ_AP023391
• Coordinates: 1237046..1237708 (-)
• Length: 220 a.a.
• NCBI ID: WP_184493068.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DAT299
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1232046..1242708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7677_RS06060 (DAT299_11600)	-	1232924..1233751 (-)	828	WP_184493066.1	hypothetical protein	-
H7677_RS06065 (DAT299_11610)	-	1233845..1234501 (-)	657	WP_023370708.1	CBS domain-containing protein	-
H7677_RS06070 (DAT299_11620)	-	1234680..1234823 (-)	144	WP_002935351.1	transposase	-
H7677_RS06075 (DAT299_11630)	comEC/celB	1234825..1237062 (-)	2238	WP_024381561.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H7677_RS06080 (DAT299_11640)	comEA/celA/cilE	1237046..1237708 (-)	663	WP_184493068.1	helix-hairpin-helix domain-containing protein	Machinery gene
H7677_RS06085 (DAT299_11650)	-	1237771..1238520 (-)	750	WP_012775039.1	lysophospholipid acyltransferase family protein	-
H7677_RS06090 (DAT299_11660)	-	1238667..1240112 (+)	1446	WP_184493070.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
H7677_RS06095 (DAT299_11670)	-	1240264..1241049 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
H7677_RS06100 (DAT299_11680)	-	1241062..1241991 (+)	930	WP_184493072.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23351.98 Da
• Isoelectric Point: 4.0997

>NTDB_id=82903 H7677_RS06080 WP_184493068.1 1237046..1237708(-) (comEA/celA/cilE) [Streptococcus suis strain DAT299]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQASSSQEQTEETSTEESEELSQLTVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKGENISVVASTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVTVE

Nucleotide

• Length: 663 bp

>NTDB_id=82903 H7677_RS06080 WP_184493068.1 1237046..1237708(-) (comEA/celA/cilE) [Streptococcus suis strain DAT299]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATATTCAGCCAACCTGCTAAGTCTGATCAAACAGGACTGACAGATTTTCCTCAAACCGAGCAAG
CTTCTAGCAGTCAGGAGCAGACGGAGGAAACCAGTACAGAAGAGAGTGAGGAGCTCAGCCAGCTAACCGTTGATGTCAAA
GGAGCGGTGGAAAAGCCTGGGTTATATACTTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTAGCCAGCAAGG
GCGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCTCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGAACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (157-218)

• SLBB domain (SLBB) (77-130)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	48.402	99.545	0.482
comEA/celA/cilE	Streptococcus pneumoniae Rx1	48.402	99.545	0.482
comEA/celA/cilE	Streptococcus pneumoniae D39	48.402	99.545	0.482
comEA/celA/cilE	Streptococcus pneumoniae R6	48.402	99.545	0.482
comEA/celA/cilE	Streptococcus mitis NCTC 12261	48.402	99.545	0.482
comEA/celA/cilE	Streptococcus mitis SK321	47.085	100	0.477
comEA	Streptococcus thermophilus LMD-9	58.642	73.636	0.432
comEA	Lactococcus lactis subsp. cremoris KW2	39.171	98.636	0.386
comEA	Bacillus subtilis subsp. subtilis str. 168	38.028	96.818	0.368