Detailed information NTG0082836

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7676_RS02225
• Genome accession: NZ_AP023390
• Coordinates: 422998..423999 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain KUN-0014944
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 417998..428999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7676_RS02200 (KUN4944_03900)	-	418672..419355 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
H7676_RS02205 (KUN4944_03910)	-	419566..420492 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
H7676_RS02210 (KUN4944_03920)	-	420637..421014 (-)	378	WP_002985686.1	VOC family protein	-
H7676_RS02215 (KUN4944_03930)	-	421025..421690 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
H7676_RS02220 (KUN4944_03940)	-	421739..422824 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
H7676_RS02225 (KUN4944_03950)	ccpA	422998..423999 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7676_RS02230 (KUN4944_03960)	-	424130..425128 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
H7676_RS02235 (KUN4944_03970)	-	425130..426464 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
H7676_RS02240 (KUN4944_03980)	thrS	426886..428829 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=82836 H7676_RS02225 WP_002985680.1 422998..423999(+) (ccpA) [Streptococcus pyogenes strain KUN-0014944]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=82836 H7676_RS02225 WP_002985680.1 422998..423999(+) (ccpA) [Streptococcus pyogenes strain KUN-0014944]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559