Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   QK281_RS02395 Genome accession   NZ_CP124746
Coordinates   497821..499062 (-) Length   413 a.a.
NCBI ID   WP_043126919.1    Uniprot ID   A0AAX3P7B3
Organism   Aeromonas hydrophila strain NN-MR659     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 492821..504062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QK281_RS02365 (QK281_02365) - 493661..494845 (+) 1185 WP_282467142.1 tetratricopeptide repeat protein -
  QK281_RS02370 (QK281_02370) mutT 494854..495267 (+) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  QK281_RS02375 (QK281_02375) yacG 495328..495522 (-) 195 WP_024945432.1 DNA gyrase inhibitor YacG -
  QK281_RS02380 (QK281_02380) zapD 495532..496254 (-) 723 WP_282467143.1 cell division protein ZapD -
  QK281_RS02385 (QK281_02385) coaE 496292..496906 (-) 615 WP_043126913.1 dephospho-CoA kinase -
  QK281_RS02390 (QK281_02390) pilD 496926..497798 (-) 873 WP_282467144.1 A24 family peptidase Machinery gene
  QK281_RS02395 (QK281_02395) pilC 497821..499062 (-) 1242 WP_043126919.1 type II secretion system F family protein Machinery gene
  QK281_RS02400 (QK281_02400) pilB 499178..500884 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  QK281_RS02405 (QK281_02405) tapA 500888..501316 (-) 429 WP_044800922.1 type IVa pilus major pilin TapA -
  QK281_RS02410 (QK281_02410) nadC 501639..502496 (-) 858 WP_282467145.1 carboxylating nicotinate-nucleotide diphosphorylase -
  QK281_RS02415 (QK281_02415) - 502502..502972 (-) 471 WP_024944772.1 retropepsin-like aspartic protease -
  QK281_RS02420 (QK281_02420) ampD 503120..503692 (+) 573 WP_124251318.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45438.58 Da        Isoelectric Point: 9.8637

>NTDB_id=827891 QK281_RS02395 WP_043126919.1 497821..499062(-) (pilC) [Aeromonas hydrophila strain NN-MR659]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LSIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=827891 QK281_RS02395 WP_043126919.1 497821..499062(-) (pilC) [Aeromonas hydrophila strain NN-MR659]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAACCGCAAGGGCCA
GAAGGTCTCTGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCAGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCGCTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCCCTAGAGACCATCTACGATCGTATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATATTGGT
GGCCATTGTCGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGTTTCGGCGCCGAAC
TGCCCATCTTCACCCAGTTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTTTCCATCTTTCTCTACGTTCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCTGCCGGTA
TTCCACTGGTGGATGCCTTGGTTTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTAGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.071

95.884

0.547
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

51.889

96.126

0.499
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40

98.063

0.392
  pilG Neisseria meningitidis 44/76-A

39.753

98.063

0.39
  pilC Thermus thermophilus HB27

37.75

96.852

0.366