Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QFC96_RS03415 Genome accession   NZ_CP123581
Coordinates   659563..660438 (+) Length   291 a.a.
NCBI ID   WP_004270904.1    Uniprot ID   -
Organism   Latilactobacillus curvatus strain ZHA1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 654563..665438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFC96_RS03375 (QFC96_03375) - 654668..655495 (-) 828 WP_004265312.1 LysR family transcriptional regulator -
  QFC96_RS03380 (QFC96_03380) - 655604..656617 (+) 1014 WP_004265264.1 YeiH family protein -
  QFC96_RS03385 (QFC96_03385) - 656708..656947 (-) 240 WP_004270892.1 cytochrome b5 domain-containing protein -
  QFC96_RS03390 (QFC96_03390) - 657142..657477 (+) 336 WP_275780570.1 hypothetical protein -
  QFC96_RS03400 (QFC96_03400) - 657658..658035 (-) 378 WP_056965888.1 hypothetical protein -
  QFC96_RS03405 (QFC96_03405) - 658138..658638 (+) 501 WP_056965890.1 VanZ family protein -
  QFC96_RS03410 (QFC96_03410) - 658728..659459 (+) 732 WP_004270897.1 YebC/PmpR family DNA-binding transcriptional regulator -
  QFC96_RS03415 (QFC96_03415) comGA 659563..660438 (+) 876 WP_004270904.1 competence type IV pilus ATPase ComGA Machinery gene
  QFC96_RS03420 (QFC96_03420) comGB 660428..661429 (+) 1002 WP_283534321.1 type II secretion system F family protein Machinery gene
  QFC96_RS03425 (QFC96_03425) comGC 661426..661734 (+) 309 WP_004270901.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  QFC96_RS03430 (QFC96_03430) - 661715..662158 (+) 444 WP_039099484.1 type II secretion system protein -
  QFC96_RS03435 (QFC96_03435) - 662145..662450 (+) 306 WP_283534322.1 hypothetical protein -
  QFC96_RS03440 (QFC96_03440) - 662521..662901 (+) 381 WP_004270914.1 ComGF family competence protein -
  QFC96_RS03445 (QFC96_03445) - 662879..663202 (+) 324 WP_254670611.1 hypothetical protein -
  QFC96_RS03450 (QFC96_03450) - 663318..664337 (+) 1020 WP_307722871.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 31998.79 Da        Isoelectric Point: 5.5654

>NTDB_id=821368 QFC96_RS03415 WP_004270904.1 659563..660438(+) (comGA) [Latilactobacillus curvatus strain ZHA1]
MAEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQGGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQVMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVDGHNVAAHYELATAQQLEEAVHED

Nucleotide


Download         Length: 876 bp        

>NTDB_id=821368 QFC96_RS03415 WP_004270904.1 659563..660438(+) (comGA) [Latilactobacillus curvatus strain ZHA1]
ATGGCCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGGGGGGATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGCGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAGTCATGCAAGATAAGATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCTTTCTTACAGTTACAGGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTTTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCTGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGACGGCCACAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Latilactobacillus sakei subsp. sakei 23K

69.534

95.876

0.667
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

42.647

93.471

0.399
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

42.222

92.784

0.392
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

41.199

91.753

0.378
  comGA/cglA/cilD Streptococcus pneumoniae R6

41.199

91.753

0.378
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

41.199

91.753

0.378
  comGA/cglA/cilD Streptococcus pneumoniae D39

41.199

91.753

0.378
  comGA Lactococcus lactis subsp. cremoris KW2

41.221

90.034

0.371
  comYA Streptococcus gordonii str. Challis substr. CH1

38.828

93.814

0.364
  comYA Streptococcus mutans UA140

39.326

91.753

0.361
  comYA Streptococcus mutans UA159

39.326

91.753

0.361