Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   R8613_RS09620 Genome accession   NZ_AP026919
Coordinates   1837167..1838423 (-) Length   418 a.a.
NCBI ID   WP_000642709.1    Uniprot ID   C1CGM5
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1832167..1843423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS09595 (PC0012_18610) - 1832224..1832430 (-) 207 WP_000366087.1 hypothetical protein -
  R8613_RS09600 (PC0012_18620) - 1832417..1832578 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  R8613_RS09605 (PC0012_18630) lytA 1832937..1833893 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R8613_RS09610 (PC0012_18640) - 1834269..1835639 (-) 1371 WP_001036293.1 MATE family efflux transporter -
  R8613_RS09615 (PC0012_18650) recA 1835946..1837112 (-) 1167 WP_001085463.1 recombinase RecA -
  R8613_RS09620 (PC0012_18660) cinA 1837167..1838423 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  R8613_RS09625 (PC0012_18670) brpA 1838508..1839524 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8613_RS09630 (PC0012_18680) - 1839532..1840050 (-) 519 WP_050116027.1 GNAT family N-acetyltransferase -
  R8613_RS09635 (PC0012_18690) tsaE 1840040..1840483 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8613_RS09640 (PC0012_18700) comM 1840569..1841189 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8613_RS09645 (PC0012_18710) - 1841571..1842434 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  R8613_RS09650 (PC0012_18720) - 1842626..1842796 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  R8613_RS09655 (PC0012_18730) pneA1 1842899..1843123 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  R8613_RS09660 (PC0012_18740) pneA2 1843130..1843318 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45075.48 Da        Isoelectric Point: 4.6064

>NTDB_id=81994 R8613_RS09620 WP_000642709.1 1837167..1838423(-) (cinA) [Streptococcus pneumoniae strain PZ900700012]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=81994 R8613_RS09620 WP_000642709.1 1837167..1838423(-) (cinA) [Streptococcus pneumoniae strain PZ900700012]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CGM5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae R36A

99.282

100

0.993
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

94.019

100

0.94
  cinA Streptococcus mitis NCTC 12261

93.78

100

0.938
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment