Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8613_RS09640 Genome accession   NZ_AP026919
Coordinates   1840569..1841189 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0H2URP6
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1835569..1846189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS09615 (PC0012_18650) recA 1835946..1837112 (-) 1167 WP_001085463.1 recombinase RecA -
  R8613_RS09620 (PC0012_18660) cinA 1837167..1838423 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  R8613_RS09625 (PC0012_18670) brpA 1838508..1839524 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8613_RS09630 (PC0012_18680) - 1839532..1840050 (-) 519 WP_050116027.1 GNAT family N-acetyltransferase -
  R8613_RS09635 (PC0012_18690) tsaE 1840040..1840483 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8613_RS09640 (PC0012_18700) comM 1840569..1841189 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8613_RS09645 (PC0012_18710) - 1841571..1842434 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  R8613_RS09650 (PC0012_18720) - 1842626..1842796 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  R8613_RS09655 (PC0012_18730) pneA1 1842899..1843123 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  R8613_RS09660 (PC0012_18740) pneA2 1843130..1843318 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=81995 R8613_RS09640 WP_000839908.1 1840569..1841189(-) (comM) [Streptococcus pneumoniae strain PZ900700012]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=81995 R8613_RS09640 WP_000839908.1 1840569..1841189(-) (comM) [Streptococcus pneumoniae strain PZ900700012]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACTCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment