Detailed information
Bioinformatically predicted
Overview
| Name | comGC | Type | Machinery gene |
| Locus tag | QAO25_RS02940 | Genome accession | NZ_CP123095 |
| Coordinates | 554335..554646 (+) | Length | 103 a.a. |
| NCBI ID | WP_000472256.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain MRSA-COL | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 541743..599145 | 554335..554646 | within | 0 |
Gene organization within MGE regions
Location: 541743..599145
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QAO25_RS02870 (QAO25_02870) | - | 542494..543279 (+) | 786 | WP_001213908.1 | metal ABC transporter ATP-binding protein | - |
| QAO25_RS02875 (QAO25_02875) | - | 543321..544184 (+) | 864 | WP_000564316.1 | metal ABC transporter permease | - |
| QAO25_RS02880 (QAO25_02880) | - | 544171..544581 (+) | 411 | WP_001095260.1 | Fur family transcriptional regulator | - |
| QAO25_RS02885 (QAO25_02885) | - | 544857..545456 (+) | 600 | WP_000863556.1 | superoxide dismutase | - |
| QAO25_RS02890 (QAO25_02890) | - | 545577..547652 (+) | 2076 | WP_000919772.1 | peptidoglycan D,D-transpeptidase FtsI family protein | - |
| QAO25_RS02895 (QAO25_02895) | rpmG | 547765..547914 (+) | 150 | WP_001265709.1 | 50S ribosomal protein L33 | - |
| QAO25_RS02900 (QAO25_02900) | - | 548123..548662 (+) | 540 | WP_000164545.1 | 5-formyltetrahydrofolate cyclo-ligase | - |
| QAO25_RS02905 (QAO25_02905) | - | 548674..550137 (+) | 1464 | WP_001017867.1 | rhomboid family protein | - |
| QAO25_RS02910 (QAO25_02910) | - | 550118..550321 (+) | 204 | WP_000087561.1 | YqgQ family protein | - |
| QAO25_RS02915 (QAO25_02915) | - | 550318..551304 (+) | 987 | WP_000161314.1 | ROK family glucokinase | - |
| QAO25_RS02920 (QAO25_02920) | - | 551304..551633 (+) | 330 | WP_001018871.1 | MTH1187 family thiamine-binding protein | - |
| QAO25_RS02925 (QAO25_02925) | - | 551630..552253 (+) | 624 | WP_001223008.1 | MBL fold metallo-hydrolase | - |
| QAO25_RS02930 (QAO25_02930) | comGA | 552305..553279 (+) | 975 | WP_000697228.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| QAO25_RS02935 (QAO25_02935) | comGB | 553251..554321 (+) | 1071 | WP_000775708.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| QAO25_RS02940 (QAO25_02940) | comGC | 554335..554646 (+) | 312 | WP_000472256.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| QAO25_RS02945 (QAO25_02945) | comGD | 554624..555070 (+) | 447 | WP_001790850.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| QAO25_RS02950 (QAO25_02950) | comGE | 555057..555356 (+) | 300 | WP_000844413.1 | hypothetical protein | Machinery gene |
| QAO25_RS02955 (QAO25_02955) | comGF | 555274..555771 (+) | 498 | WP_001789864.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| QAO25_RS02960 (QAO25_02960) | - | 555868..556014 (+) | 147 | WP_001789879.1 | hypothetical protein | - |
| QAO25_RS02965 (QAO25_02965) | - | 556004..556528 (+) | 525 | WP_001015117.1 | shikimate kinase | - |
| QAO25_RS02970 (QAO25_02970) | gcvT | 556687..557778 (+) | 1092 | WP_000093349.1 | glycine cleavage system aminomethyltransferase GcvT | - |
| QAO25_RS02975 (QAO25_02975) | gcvPA | 557798..559144 (+) | 1347 | WP_000019693.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPA | - |
| QAO25_RS02980 (QAO25_02980) | gcvPB | 559137..560609 (+) | 1473 | WP_000202192.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPB | - |
| QAO25_RS02985 (QAO25_02985) | - | 560974..561360 (-) | 387 | WP_001276571.1 | rhodanese-like domain-containing protein | - |
| QAO25_RS02990 (QAO25_02990) | - | 561518..562348 (+) | 831 | WP_000141109.1 | biotin/lipoate A/B protein ligase family protein | - |
| QAO25_RS02995 (QAO25_02995) | - | 562412..562630 (-) | 219 | WP_001244298.1 | SA1362 family protein | - |
| QAO25_RS03000 (QAO25_03000) | - | 562644..563225 (-) | 582 | WP_000737686.1 | hypothetical protein | - |
| QAO25_RS03005 (QAO25_03005) | - | 563330..564391 (+) | 1062 | WP_000087107.1 | M24 family metallopeptidase | - |
| QAO25_RS03010 (QAO25_03010) | efp | 564417..564974 (+) | 558 | WP_000626504.1 | elongation factor P | - |
| QAO25_RS03015 (QAO25_03015) | - | 565369..565653 (+) | 285 | WP_000134545.1 | hypothetical protein | - |
| QAO25_RS03020 (QAO25_03020) | - | 565804..566124 (+) | 321 | WP_000805733.1 | DUF961 family protein | - |
| QAO25_RS03025 (QAO25_03025) | - | 566138..566440 (+) | 303 | WP_000386891.1 | hypothetical protein | - |
| QAO25_RS03030 (QAO25_03030) | - | 566615..567706 (+) | 1092 | WP_000172943.1 | replication initiation factor domain-containing protein | - |
| QAO25_RS03035 (QAO25_03035) | - | 567767..568822 (+) | 1056 | WP_000692002.1 | conjugal transfer protein | - |
| QAO25_RS03040 (QAO25_03040) | - | 568827..569087 (+) | 261 | WP_000015639.1 | TcpD family membrane protein | - |
| QAO25_RS03045 (QAO25_03045) | - | 569099..569482 (+) | 384 | WP_000358144.1 | TcpE family conjugal transfer membrane protein | - |
| QAO25_RS03050 (QAO25_03050) | - | 569517..572012 (+) | 2496 | WP_001049264.1 | ATP-binding protein | - |
| QAO25_RS03055 (QAO25_03055) | - | 572066..573424 (+) | 1359 | WP_001251212.1 | FtsK/SpoIIIE domain-containing protein | - |
| QAO25_RS03060 (QAO25_03060) | - | 573429..575276 (+) | 1848 | WP_000681143.1 | CD3337/EF1877 family mobilome membrane protein | - |
| QAO25_RS03065 (QAO25_03065) | - | 575266..576312 (+) | 1047 | WP_000247469.1 | CHAP domain-containing protein | - |
| QAO25_RS03070 (QAO25_03070) | - | 576319..576909 (+) | 591 | WP_000810443.1 | hypothetical protein | - |
| QAO25_RS03075 (QAO25_03075) | - | 576965..577306 (+) | 342 | WP_001255377.1 | cystatin-like fold lipoprotein | - |
| QAO25_RS03080 (QAO25_03080) | - | 577415..577918 (+) | 504 | WP_000746371.1 | transposase | - |
| QAO25_RS03085 (QAO25_03085) | - | 577947..578435 (+) | 489 | WP_176318786.1 | IS30 family transposase | - |
| QAO25_RS03090 (QAO25_03090) | accB | 578790..579254 (+) | 465 | WP_001009516.1 | acetyl-CoA carboxylase biotin carboxyl carrier protein | - |
| QAO25_RS03095 (QAO25_03095) | accC | 579254..580609 (+) | 1356 | WP_000756612.1 | acetyl-CoA carboxylase biotin carboxylase subunit | - |
| QAO25_RS03100 (QAO25_03100) | - | 580624..580986 (+) | 363 | WP_000241588.1 | Asp23/Gls24 family envelope stress response protein | - |
| QAO25_RS03105 (QAO25_03105) | nusB | 581046..581435 (+) | 390 | WP_000087385.1 | transcription antitermination factor NusB | - |
| QAO25_RS03110 (QAO25_03110) | xseA | 581452..582789 (+) | 1338 | WP_001286928.1 | exodeoxyribonuclease VII large subunit | - |
| QAO25_RS03115 (QAO25_03115) | - | 582782..583012 (+) | 231 | WP_000159865.1 | exodeoxyribonuclease VII small subunit | - |
| QAO25_RS03120 (QAO25_03120) | - | 582990..583871 (+) | 882 | WP_000183378.1 | polyprenyl synthetase family protein | - |
| QAO25_RS03125 (QAO25_03125) | ahrC | 584303..584755 (+) | 453 | WP_001124985.1 | transcriptional regulator AhrC/ArgR | - |
| QAO25_RS03130 (QAO25_03130) | recN | 584771..586450 (+) | 1680 | WP_000942211.1 | DNA repair protein RecN | - |
| QAO25_RS03135 (QAO25_03135) | lpdA | 586601..588022 (+) | 1422 | WP_001291535.1 | dihydrolipoyl dehydrogenase | - |
| QAO25_RS03140 (QAO25_03140) | - | 588038..589030 (+) | 993 | WP_000568353.1 | thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha | - |
| QAO25_RS03145 (QAO25_03145) | - | 589030..590013 (+) | 984 | WP_001096642.1 | alpha-ketoacid dehydrogenase subunit beta | - |
| QAO25_RS03150 (QAO25_03150) | - | 590026..591300 (+) | 1275 | WP_000406839.1 | dihydrolipoamide acetyltransferase family protein | - |
| QAO25_RS03155 (QAO25_03155) | brxB | 591651..592088 (+) | 438 | WP_000367419.1 | bacilliredoxin BrxB | - |
| QAO25_RS03160 (QAO25_03160) | - | 592102..593082 (+) | 981 | WP_000916195.1 | aromatic acid exporter family protein | - |
| QAO25_RS03165 (QAO25_03165) | prli42 | 593209..593388 (-) | 180 | WP_001789875.1 | stressosome-associated protein Prli42 | - |
| QAO25_RS03170 (QAO25_03170) | - | 593651..594784 (+) | 1134 | WP_000606676.1 | tripeptidase T | - |
| QAO25_RS03175 (QAO25_03175) | gndA | 594852..596258 (+) | 1407 | WP_000193707.1 | NADP-dependent phosphogluconate dehydrogenase | - |
| QAO25_RS03180 (QAO25_03180) | - | 596477..596848 (+) | 372 | WP_000413437.1 | VOC family protein | - |
| QAO25_RS03185 (QAO25_03185) | - | 596787..597041 (+) | 255 | WP_001791638.1 | hypothetical protein | - |
| QAO25_RS03190 (QAO25_03190) | - | 597042..598061 (+) | 1020 | WP_000256338.1 | LacI family DNA-binding transcriptional regulator | - |
Sequence
Protein
Download Length: 103 a.a. Molecular weight: 11315.36 Da Isoelectric Point: 8.5268
>NTDB_id=818595 QAO25_RS02940 WP_000472256.1 554335..554646(+) (comGC) [Staphylococcus aureus strain MRSA-COL]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN
Nucleotide
Download Length: 312 bp
>NTDB_id=818595 QAO25_RS02940 WP_000472256.1 554335..554646(+) (comGC) [Staphylococcus aureus strain MRSA-COL]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC | Staphylococcus aureus MW2 |
100 |
100 |
1 |
| comGC | Staphylococcus aureus N315 |
100 |
100 |
1 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
46.078 |
99.029 |
0.456 |
| comGC/cglC | Streptococcus pneumoniae Rx1 |
46.078 |
99.029 |
0.456 |
| comGC/cglC | Streptococcus pneumoniae D39 |
46.078 |
99.029 |
0.456 |
| comGC/cglC | Streptococcus pneumoniae R6 |
46.078 |
99.029 |
0.456 |
| comGC/cglC | Streptococcus mitis SK321 |
51.163 |
83.495 |
0.427 |
| comGC/cglC | Streptococcus mitis NCTC 12261 |
51.163 |
83.495 |
0.427 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
42.857 |
95.146 |
0.408 |
| comYC | Streptococcus suis isolate S10 |
50 |
75.728 |
0.379 |
| comGC | Bacillus subtilis subsp. subtilis str. 168 |
41.758 |
88.35 |
0.369 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
46.341 |
79.612 |
0.369 |