Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   F6I35_RS01585 Genome accession   NZ_CP136160
Coordinates   267238..267507 (+) Length   89 a.a.
NCBI ID   WP_003039250.1    Uniprot ID   A0A418G4X7
Organism   Streptococcus anginosus strain UMB8616     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 262238..272507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS01555 (F6I35_0001555) - 262812..264851 (+) 2040 WP_150867029.1 DUF859 family phage minor structural protein -
  F6I35_RS01560 (F6I35_0001560) - 264864..265466 (+) 603 WP_150867027.1 DUF1366 domain-containing protein -
  F6I35_RS01565 (F6I35_0001565) - 265484..265789 (+) 306 WP_049507630.1 hypothetical protein -
  F6I35_RS01570 (F6I35_0001570) - 265801..266133 (+) 333 WP_049507631.1 phage holin -
  F6I35_RS01575 (F6I35_0001575) - 266135..266881 (+) 747 WP_150867025.1 CHAP domain-containing protein -
  F6I35_RS01580 (F6I35_0001580) - 266997..267236 (+) 240 WP_150867023.1 hypothetical protein -
  F6I35_RS01585 (F6I35_0001585) comGC 267238..267507 (+) 270 WP_003039250.1 competence type IV pilus major pilin ComGC Machinery gene
  F6I35_RS01590 (F6I35_0001590) comGD 267467..267895 (+) 429 WP_024053128.1 competence type IV pilus minor pilin ComGD Machinery gene
  F6I35_RS01595 (F6I35_0001595) comGE/cglE 267867..268160 (+) 294 WP_024053127.1 competence type IV pilus minor pilin ComGE Machinery gene
  F6I35_RS01600 (F6I35_0001600) comGF/cglF 268144..268581 (+) 438 WP_024053126.1 competence type IV pilus minor pilin ComGF Machinery gene
  F6I35_RS01605 (F6I35_0001605) comGG/cglG 268562..268888 (+) 327 WP_257360478.1 competence type IV pilus minor pilin ComGG Machinery gene
  F6I35_RS01610 (F6I35_0001610) comGH 268960..269913 (+) 954 WP_024053125.1 class I SAM-dependent methyltransferase Machinery gene
  F6I35_RS01615 (F6I35_0001615) - 269960..271159 (+) 1200 WP_024053124.1 acetate kinase -

Sequence

Protein


Download         Length: 89 a.a.        Molecular weight: 9791.38 Da        Isoelectric Point: 8.4759

>NTDB_id=812810 F6I35_RS01585 WP_003039250.1 267238..267507(+) (comGC) [Streptococcus anginosus strain UMB8616]
MLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGTITDKQAASYKAYYAKH
TKEARSVAD

Nucleotide


Download         Length: 270 bp        

>NTDB_id=812810 F6I35_RS01585 WP_003039250.1 267238..267507(+) (comGC) [Streptococcus anginosus strain UMB8616]
ATGTTAGTCGTGCTTCTTATCATCAGTGTTTTGATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCTGTAAC
GGAAAAAGGAAATGCAGCGGTGGTAAAAGTTGTGGAAAGCCAGGCAGAGCTGTTTGAGGTCAATCACACCAATGAAAAAG
CGACACTCTCAAAATTAGTCAACGAAGGAACGATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACAT
ACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A418G4X7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Streptococcus gordonii str. Challis substr. CH1

73.034

100

0.73
  comGC/cglC Streptococcus pneumoniae Rx1

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae D39

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae R6

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae TIGR4

65.169

100

0.652
  comGC Streptococcus mutans UA140

64.384

82.022

0.528
  comGC Streptococcus mutans UA159

64.384

82.022

0.528
  comGC/cglC Streptococcus mitis SK321

62.667

84.27

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

62.667

84.27

0.528
  comGC Streptococcus suis isolate S10

63.014

82.022

0.517
  comGC Lactococcus lactis subsp. cremoris KW2

52.632

85.393

0.449