Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   F6I35_RS01595 Genome accession   NZ_CP136160
Coordinates   267867..268160 (+) Length   97 a.a.
NCBI ID   WP_024053127.1    Uniprot ID   A0A412PLL4
Organism   Streptococcus anginosus strain UMB8616     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 262867..273160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS01560 (F6I35_0001560) - 264864..265466 (+) 603 WP_150867027.1 DUF1366 domain-containing protein -
  F6I35_RS01565 (F6I35_0001565) - 265484..265789 (+) 306 WP_049507630.1 hypothetical protein -
  F6I35_RS01570 (F6I35_0001570) - 265801..266133 (+) 333 WP_049507631.1 phage holin -
  F6I35_RS01575 (F6I35_0001575) - 266135..266881 (+) 747 WP_150867025.1 CHAP domain-containing protein -
  F6I35_RS01580 (F6I35_0001580) - 266997..267236 (+) 240 WP_150867023.1 hypothetical protein -
  F6I35_RS01585 (F6I35_0001585) comGC 267238..267507 (+) 270 WP_003039250.1 competence type IV pilus major pilin ComGC Machinery gene
  F6I35_RS01590 (F6I35_0001590) comGD 267467..267895 (+) 429 WP_024053128.1 competence type IV pilus minor pilin ComGD Machinery gene
  F6I35_RS01595 (F6I35_0001595) comGE/cglE 267867..268160 (+) 294 WP_024053127.1 competence type IV pilus minor pilin ComGE Machinery gene
  F6I35_RS01600 (F6I35_0001600) comGF/cglF 268144..268581 (+) 438 WP_024053126.1 competence type IV pilus minor pilin ComGF Machinery gene
  F6I35_RS01605 (F6I35_0001605) comGG/cglG 268562..268888 (+) 327 WP_257360478.1 competence type IV pilus minor pilin ComGG Machinery gene
  F6I35_RS01610 (F6I35_0001610) comGH 268960..269913 (+) 954 WP_024053125.1 class I SAM-dependent methyltransferase Machinery gene
  F6I35_RS01615 (F6I35_0001615) - 269960..271159 (+) 1200 WP_024053124.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10836.84 Da        Isoelectric Point: 10.6170

>NTDB_id=812812 F6I35_RS01595 WP_024053127.1 267867..268160(+) (comGE/cglE) [Streptococcus anginosus strain UMB8616]
MGNLRKQHVKGTILLEALLALAVFVTIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=812812 F6I35_RS01595 WP_024053127.1 267867..268160(+) (comGE/cglE) [Streptococcus anginosus strain UMB8616]
ATGGGAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGTGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PLL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae D39

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae R6

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae TIGR4

50.526

97.938

0.495
  comGE/cglE Streptococcus mitis NCTC 12261

49.474

97.938

0.485
  comGE/cglE Streptococcus mitis SK321

49.474

97.938

0.485
  comGE Streptococcus mutans UA140

45.455

100

0.464
  comGE Streptococcus mutans UA159

45.455

100

0.464