Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   P5S46_RS18400 Genome accession   NZ_CP120942
Coordinates   3967884..3969125 (+) Length   413 a.a.
NCBI ID   WP_277856345.1    Uniprot ID   -
Organism   Aeromonas caviae strain AC1520     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3962884..3974125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5S46_RS18375 (P5S46_18375) ampD 3963258..3963830 (-) 573 WP_277856342.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  P5S46_RS18380 (P5S46_18380) - 3963959..3964429 (+) 471 WP_042015101.1 retropepsin-like aspartic protease -
  P5S46_RS18385 (P5S46_18385) nadC 3964433..3965296 (+) 864 WP_128341717.1 carboxylating nicotinate-nucleotide diphosphorylase -
  P5S46_RS18390 (P5S46_18390) - 3965607..3966050 (+) 444 WP_277856343.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  P5S46_RS18395 (P5S46_18395) pilB 3966050..3967756 (+) 1707 WP_277856344.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  P5S46_RS18400 (P5S46_18400) pilC 3967884..3969125 (+) 1242 WP_277856345.1 type II secretion system F family protein Machinery gene
  P5S46_RS18405 (P5S46_18405) pilD 3969203..3970078 (+) 876 WP_277856346.1 A24 family peptidase Machinery gene
  P5S46_RS18410 (P5S46_18410) coaE 3970097..3970711 (+) 615 WP_042864857.1 dephospho-CoA kinase -
  P5S46_RS18415 (P5S46_18415) zapD 3970749..3971471 (+) 723 WP_010675825.1 cell division protein ZapD -
  P5S46_RS18420 (P5S46_18420) yacG 3971482..3971676 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  P5S46_RS18425 (P5S46_18425) mutT 3971734..3972138 (-) 405 WP_174213873.1 8-oxo-dGTP diphosphatase MutT -
  P5S46_RS18430 (P5S46_18430) - 3972147..3973331 (-) 1185 WP_277856347.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45469.38 Da        Isoelectric Point: 9.9380

>NTDB_id=809483 P5S46_RS18400 WP_277856345.1 3967884..3969125(+) (pilC) [Aeromonas caviae strain AC1520]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFFYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=809483 P5S46_RS18400 WP_277856345.1 3967884..3969125(+) (pilC) [Aeromonas caviae strain AC1520]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCAGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCCCGCGGCCACGAGAAAGCAGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTATGACCGTATC
GCCATCTACCGCGAGAAAAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTCACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCGGCT
CTCGCCGTCTTCTTCTATGTGCGGGCCTGGCGAAAATCCCAGAAAGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCTGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TACCGCTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGACCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Acinetobacter baylyi ADP1

50.728

99.758

0.506
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.226

96.368

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

39

96.852

0.378