Detailed information NTG0799267

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: P1T45_RS10335
• Genome accession: NZ_CP119427
• Coordinates: 1949814..1950551 (-)
• Length: 245 a.a.
• NCBI ID: WP_308695451.1
• Uniprot ID: -
• Organism: Streptococcus parauberis strain KSP45
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1944814..1955551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1T45_RS10315 (P1T45_10320)	-	1945447..1946259 (-)	813	WP_003105313.1	YidC/Oxa1 family membrane protein insertase	-
P1T45_RS10320 (P1T45_10325)	rnpA	1946243..1946608 (-)	366	WP_003106032.1	ribonuclease P protein component	-
P1T45_RS10325 (P1T45_10330)	argH	1946693..1948078 (-)	1386	WP_004347270.1	argininosuccinate lyase	-
P1T45_RS10330 (P1T45_10335)	-	1948118..1949320 (-)	1203	WP_003107761.1	argininosuccinate synthase	-
P1T45_RS10335 (P1T45_10340)	comE/blpR	1949814..1950551 (-)	738	WP_308695451.1	LytTR family DNA-binding domain-containing protein	Regulator
P1T45_RS10340 (P1T45_10345)	-	1950554..1951585 (-)	1032	WP_004347269.1	GHKL domain-containing protein	-
P1T45_RS10345 (P1T45_10350)	-	1951865..1953211 (-)	1347	WP_037620084.1	GHKL domain-containing protein	-
P1T45_RS10350 (P1T45_10355)	-	1953376..1954695 (-)	1320	WP_004347268.1	GHKL domain-containing protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28879.19 Da
• Isoelectric Point: 4.7047

>NTDB_id=799267 P1T45_RS10335 WP_308695451.1 1949814..1950551(-) (comE/blpR) [Streptococcus parauberis strain KSP45]
MNIFILEDDFIQQTRIESAIESILKENNISCKFMEVFSNPQKLYDAILEKGDHQIFFLDIEIQGESRKGLELATEIRQKD
PNAVIVFVTTHSEFAPISYKYKVSALDFIDKSVDTKQFKEQIQECICYTNEMMSKNEPEDLFIFETPQTRLKMPLKDILY
FATSTTPHKVCLWTQTERLEFYGKLSEIQEVAPELFLCHRSYLINLDNVVRIDKFNQLVYFENGDDVMVSRLKMKSLIEK
WQELH

Nucleotide

• Length: 738 bp

>NTDB_id=799267 P1T45_RS10335 WP_308695451.1 1949814..1950551(-) (comE/blpR) [Streptococcus parauberis strain KSP45]
ATGAACATTTTTATATTAGAAGATGATTTTATCCAGCAAACTCGAATAGAATCAGCAATTGAAAGTATCCTCAAAGAAAA
TAATATAAGCTGCAAATTTATGGAAGTTTTTTCAAATCCCCAAAAGCTGTATGATGCCATCCTAGAAAAAGGTGACCATC
AGATTTTTTTCCTTGATATCGAAATTCAAGGAGAATCACGCAAGGGCTTGGAATTAGCAACTGAAATTCGTCAAAAAGAT
CCAAATGCAGTTATTGTTTTTGTGACGACTCATTCAGAGTTTGCTCCAATTTCCTATAAATATAAAGTGTCAGCACTTGA
TTTTATTGATAAGTCGGTTGATACTAAGCAATTTAAGGAACAAATACAAGAATGTATTTGTTACACGAATGAGATGATGT
CAAAAAACGAACCAGAAGATCTCTTTATTTTTGAGACACCTCAAACTAGACTAAAAATGCCACTAAAGGATATCCTTTAC
TTTGCAACTTCAACAACACCCCATAAAGTTTGTTTGTGGACACAAACAGAACGACTCGAGTTTTATGGTAAATTATCTGA
AATTCAAGAAGTAGCACCAGAGTTATTTCTCTGTCACCGTTCTTACTTGATTAATCTTGATAATGTTGTTCGAATTGATA
AATTTAATCAATTAGTCTATTTTGAAAATGGTGATGATGTTATGGTCTCACGACTCAAAATGAAAAGTTTAATTGAAAAA
TGGCAAGAATTACACTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	51.681	97.143	0.502
comE/comE2	Streptococcus equinus JB1	43.033	99.592	0.429
comE/comE1	Streptococcus equinus JB1	42.857	97.143	0.416
comE/comE2	Streptococcus gordonii strain NCTC7865	39.918	99.184	0.396
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.918	99.184	0.396
comE	Streptococcus pneumoniae Rx1	37.19	98.776	0.367
comE	Streptococcus pneumoniae D39	37.19	98.776	0.367
comE	Streptococcus pneumoniae R6	37.19	98.776	0.367
comE	Streptococcus pneumoniae TIGR4	37.19	98.776	0.367
comE	Streptococcus mitis SK321	37.344	98.367	0.367
comE	Streptococcus mitis NCTC 12261	37.344	98.367	0.367
comE	Streptococcus infantis strain Atu-4	36.777	98.776	0.363