Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PXH68_RS09415 Genome accession   NZ_CP118733
Coordinates   2052043..2053224 (-) Length   393 a.a.
NCBI ID   WP_248027827.1    Uniprot ID   A0AA96ZYY6
Organism   Streptococcus suivaginalis strain 29896     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2047043..2058224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXH68_RS09385 (PXH68_09370) comR 2048124..2049023 (-) 900 WP_248027822.1 helix-turn-helix domain-containing protein Regulator
  PXH68_RS09390 (PXH68_09375) - 2049137..2049463 (-) 327 WP_205030924.1 DUF1292 domain-containing protein -
  PXH68_RS09395 (PXH68_09380) ruvX 2049474..2049893 (-) 420 WP_158456249.1 Holliday junction resolvase RuvX -
  PXH68_RS09400 (PXH68_09385) - 2049893..2050159 (-) 267 WP_158456247.1 IreB family regulatory phosphoprotein -
  PXH68_RS09405 (PXH68_09390) spx 2050273..2050671 (-) 399 WP_158456245.1 transcriptional regulator Spx -
  PXH68_RS09410 (PXH68_09395) recA 2050848..2051993 (-) 1146 WP_248027824.1 recombinase RecA Machinery gene
  PXH68_RS09415 (PXH68_09400) cinA 2052043..2053224 (-) 1182 WP_248027827.1 competence/damage-inducible protein A Machinery gene
  PXH68_RS09420 (PXH68_09405) - 2053658..2053831 (+) 174 Protein_1817 helix-turn-helix domain-containing protein -
  PXH68_RS09425 (PXH68_09410) - 2053961..2054512 (-) 552 WP_248027831.1 DNA-3-methyladenine glycosylase I -
  PXH68_RS09430 (PXH68_09415) ruvA 2055081..2055671 (-) 591 WP_248027833.1 Holliday junction branch migration protein RuvA -
  PXH68_RS09435 (PXH68_09420) mutL 2055712..2057655 (-) 1944 WP_248027835.1 DNA mismatch repair endonuclease MutL -
  PXH68_RS09440 (PXH68_09425) - 2057711..2057884 (-) 174 WP_205030916.1 hypothetical protein -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42643.54 Da        Isoelectric Point: 4.5037

>NTDB_id=794654 PXH68_RS09415 WP_248027827.1 2052043..2053224(-) (cinA) [Streptococcus suivaginalis strain 29896]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNANRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LAAFLGRNLVFDDEAMAKLDRFFASRPGRVRTPNNERQAQIVEGSFALQNPTGLAVGGMIEQDGVSYVVLPGPPSELKAM
FTRSLQPLLIQSSQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEVADQRLNQLEEE
ILQRDKLADYFYAYGEENSLVQTVAVRLVAKQESIAIVEQGTGGLLQAELSLALENQAYFSGGKVIGQQGTGSGRCWEEA
GRIRQDLQADLGLSVSVLIKPESTEDNVLAKVCLALASTSGIAQMEVDLGGYSWSHIRQLAVMQALDFVRKTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=794654 PXH68_RS09415 WP_248027827.1 2052043..2053224(-) (cinA) [Streptococcus suivaginalis strain 29896]
ATGAAAGCAGAACTAATCGCGGTTGGGACAGAGATTTTGACAGGTCAAATCGTTAATACAAACGCCCAGTTTCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTACTTCCACACAGCTGTGGGGGATAATGCAAACAGGCTTTTGTCTGTTCTGG
AGGTGGCTAGCCAACGCAGTGATTTGGTTATCTTGTGTGGAGGTCTGGGGCCAACGGAAGACGACTTGACCAAGCAGACC
TTGGCGGCCTTCTTAGGTAGAAACTTGGTTTTTGATGATGAGGCTATGGCAAAATTAGACCGCTTTTTTGCCAGTCGGCC
AGGTCGTGTCCGTACGCCTAACAATGAACGTCAGGCACAGATTGTTGAGGGAAGCTTTGCCTTGCAAAATCCAACTGGTT
TGGCAGTTGGAGGCATGATTGAGCAAGATGGGGTGTCCTATGTTGTCTTACCTGGTCCGCCTAGCGAACTTAAGGCTATG
TTTACAAGAAGTTTACAGCCCTTGCTTATTCAGTCAAGTCAACAACTATACTCTCGTGTCCTACGCTTTTTTGGAATAGG
GGAAAGTCAGTTGGTGACTGTTTTAGCAGATTTGATTGACAAGCAAACAGACCCGACTCTTGCTCCGTATGCAAAAGTGG
GAGAGGTCACGCTTCGATTATCTACCAAGGCAACTAGCCAAGAAGTTGCAGATCAACGTCTGAATCAGTTGGAAGAAGAA
ATCTTGCAACGTGACAAACTGGCAGATTACTTCTATGCCTACGGTGAAGAAAATAGCCTGGTACAAACGGTAGCGGTTCG
GTTGGTGGCGAAACAAGAAAGCATAGCCATCGTGGAGCAGGGTACAGGTGGCCTCTTGCAGGCTGAATTGAGCCTGGCTC
TGGAAAATCAGGCTTATTTTAGCGGTGGGAAAGTCATCGGTCAGCAGGGAACGGGTTCGGGCAGGTGCTGGGAAGAAGCT
GGTCGCATTCGGCAGGATTTGCAAGCGGATTTGGGGTTGTCTGTGTCGGTGCTTATCAAGCCAGAATCGACAGAGGACAA
CGTCCTTGCCAAGGTTTGTCTTGCTCTGGCAAGTACCTCTGGGATTGCCCAAATGGAGGTGGACCTGGGAGGGTATTCCT
GGAGTCACATTCGTCAATTGGCGGTGATGCAGGCTCTTGATTTCGTACGAAAAACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(313-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

84.224

100

0.842
  cinA Streptococcus mitis SK321

57.212

100

0.606
  cinA Streptococcus mitis NCTC 12261

56.938

100

0.606
  cinA Streptococcus pneumoniae TIGR4

56.971

100

0.603
  cinA Streptococcus pneumoniae Rx1

56.971

100

0.603
  cinA Streptococcus pneumoniae R6

56.971

100

0.603
  cinA Streptococcus pneumoniae D39

56.731

100

0.601
  cinA Streptococcus mutans UA159

57.178

100

0.598
  cinA Bacillus subtilis subsp. subtilis str. 168

40.194

100

0.422