Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PWO56_RS01980 Genome accession   NZ_CP118699
Coordinates   409237..410478 (-) Length   413 a.a.
NCBI ID   WP_043126919.1    Uniprot ID   A0AAX3P7B3
Organism   Aeromonas hydrophila strain K522     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 404237..415478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWO56_RS01950 (PWO56_01950) - 405078..406262 (+) 1185 WP_077095243.1 tetratricopeptide repeat protein -
  PWO56_RS01955 (PWO56_01955) mutT 406271..406684 (+) 414 WP_179101298.1 8-oxo-dGTP diphosphatase MutT -
  PWO56_RS01960 (PWO56_01960) yacG 406745..406939 (-) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  PWO56_RS01965 (PWO56_01965) zapD 406949..407671 (-) 723 WP_024945431.1 cell division protein ZapD -
  PWO56_RS01970 (PWO56_01970) coaE 407709..408323 (-) 615 WP_077095241.1 dephospho-CoA kinase -
  PWO56_RS01975 (PWO56_01975) pilD 408342..409214 (-) 873 WP_077095240.1 A24 family peptidase Machinery gene
  PWO56_RS01980 (PWO56_01980) pilC 409237..410478 (-) 1242 WP_043126919.1 type II secretion system F family protein Machinery gene
  PWO56_RS01985 (PWO56_01985) pilB 410594..412300 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  PWO56_RS01990 (PWO56_01990) - 412304..412744 (-) 441 WP_077095239.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  PWO56_RS01995 (PWO56_01995) nadC 413067..413924 (-) 858 WP_077095238.1 carboxylating nicotinate-nucleotide diphosphorylase -
  PWO56_RS02000 (PWO56_02000) - 413930..414400 (-) 471 WP_024944772.1 retropepsin-like aspartic protease -
  PWO56_RS02005 (PWO56_02005) ampD 414548..415120 (+) 573 WP_077095237.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45438.58 Da        Isoelectric Point: 9.8637

>NTDB_id=794443 PWO56_RS01980 WP_043126919.1 409237..410478(-) (pilC) [Aeromonas hydrophila strain K522]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LSIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=794443 PWO56_RS01980 WP_043126919.1 409237..410478(-) (pilC) [Aeromonas hydrophila strain K522]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTAAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AAGTAAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCACTGCGCCGCCATCCCC
GCCACTTTGACGATCTTTATTGCGATCTGGTGGAGGCTGGCGAGCAGTCCGGCGCTCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTTGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCATCTTTACCCAGTTTGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTTTCCATCTTTCTCTACGTTCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGTACCCTCTCCACCACCTTCTCTGCCGGTA
TCCCGCTGGTGGATGCCTTGGTTTCTGCAGCTGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAAATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTACTGGTTGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.071

95.884

0.547
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

51.889

96.126

0.499
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40

98.063

0.392
  pilG Neisseria meningitidis 44/76-A

39.753

98.063

0.39
  pilC Thermus thermophilus HB27

37.75

96.852

0.366