Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   H7R46_RS16955 Genome accession   NZ_AP022302
Coordinates   3571691..3572917 (+) Length   408 a.a.
NCBI ID   WP_042783374.1    Uniprot ID   A0A022J0M4
Organism   Acinetobacter sp. BEC1-S18-ESBL-01     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3566691..3577917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7R46_RS16920 (BE1S18E01_32900) rimP 3567362..3567886 (-) 525 WP_002114922.1 ribosome maturation factor RimP -
  H7R46_RS16940 (BE1S18E01_32910) secG 3568524..3568853 (-) 330 WP_002115012.1 preprotein translocase subunit SecG -
  H7R46_RS16945 (BE1S18E01_32920) tpiA 3568866..3569660 (-) 795 WP_032012469.1 triose-phosphate isomerase -
  H7R46_RS16950 (BE1S18E01_32930) pilB 3569952..3571664 (+) 1713 WP_032012470.1 type IV-A pilus assembly ATPase PilB Machinery gene
  H7R46_RS16955 (BE1S18E01_32940) pilC 3571691..3572917 (+) 1227 WP_042783374.1 type II secretion system F family protein Machinery gene
  H7R46_RS16960 (BE1S18E01_32950) pilD 3572917..3573777 (+) 861 WP_032012472.1 prepilin peptidase Machinery gene
  H7R46_RS16965 (BE1S18E01_32960) coaE 3573779..3574375 (+) 597 WP_032012473.1 dephospho-CoA kinase -
  H7R46_RS16970 (BE1S18E01_32970) - 3574372..3575286 (-) 915 WP_042783373.1 DMT family transporter -
  H7R46_RS16975 (BE1S18E01_32980) rlmB 3575322..3576071 (-) 750 WP_005079348.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  H7R46_RS16980 (BE1S18E01_32990) - 3576174..3576500 (-) 327 WP_002115102.1 pyrimidine/purine nucleoside phosphorylase -
  H7R46_RS16985 (BE1S18E01_33000) - 3576577..3577887 (-) 1311 WP_032012475.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45036.46 Da        Isoelectric Point: 9.8207

>NTDB_id=77657 H7R46_RS16955 WP_042783374.1 3571691..3572917(+) (pilC) [Acinetobacter sp. BEC1-S18-ESBL-01]
MTVKKAQMMPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEGLFKKKVSTLDITIFTRQLAT
MMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVEGGSTFASALRKYPQHFDNLFCSLVESGEHSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAVVVTIILMVKVVPVFQDLFSSFGADLPAFTQMVVNMSKWMQEYWFIMIIVIGAVIA
AFLEAKKRSKKFRDGLDKLTLKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVIYEEAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVI

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=77657 H7R46_RS16955 WP_042783374.1 3571691..3572917(+) (pilC) [Acinetobacter sp. BEC1-S18-ESBL-01]
ATGACTGTCAAAAAGGCACAAATGATGCCGACTTTTGCTTATGAAGGGGTTGACCGTAAGGGCGTAAAAATTAAGGGCGA
ACTTCCAGCTAAGAATATGGCCTTAGCCAAAGTCACCCTACGCAAACAAGGTGTAACTGTCCGTAATATTCGGGAAAAGC
GTAAAAATATTCTTGAGGGTTTATTCAAGAAAAAAGTATCAACACTCGATATAACAATTTTTACTCGACAACTTGCAACG
ATGATGAAAGCAGGTGTGCCACTGGTACAAGGCTTTGAAATTGTAGCGGAGGGTCTAGAAAACCCAGCCATGCGCGAGGT
GGTCCTCGGGATTAAAGGTGAAGTTGAAGGTGGTAGTACCTTTGCTTCCGCTTTAAGAAAGTATCCTCAACACTTCGATA
ACTTGTTTTGTTCTCTTGTAGAGTCTGGCGAACACTCTGGTGCGCTTGAAACCATGTTGGACCGTGTGGCAATTTACAAA
GAAAAAAGTGAATTACTTAAGCAGAAAATTAAGAAGGCTATGAAATATCCAGCAACGGTTATTGTAGTTGCTGTGGTTGT
TACCATTATTTTGATGGTTAAAGTAGTTCCTGTTTTCCAAGATCTGTTTTCTTCTTTTGGTGCAGATTTACCTGCATTCA
CCCAAATGGTCGTAAATATGTCGAAATGGATGCAGGAATACTGGTTCATTATGATTATTGTGATTGGAGCAGTGATTGCT
GCTTTTCTGGAAGCCAAGAAGCGCAGTAAAAAATTCCGTGATGGATTAGATAAACTTACACTGAAACTACCTATCTTTGG
TGATCTGGTTTATAAGGCGATTATTGCCCGTTATAGCCGTACTTTAGCCACCACGTTTGCCGCTGGTGTTCCGCTCATTG
ATGCGCTTGAGTCAACGGCTGGTGCAACCAACAATGTCATTTATGAAGAAGCCGTCATGAAAATTCGTGAAGATGTTGCT
ACTGGTCAACAACTCCAATTTGCAATGCGTGTTTCAAATCGTTTTCCATCTATGGCTATACAAATGGTCGCAATTGGTGA
AGAATCTGGTGCGCTAGACAGCATGCTCGATAAAGTTGCTACTTATTATGAAAATGAAGTTGATAATGCCGTTGATGGTT
TAACTTCAATGATGGAACCTTTAATCATGGCAATTTTAGGGGTGCTCGTAGGTGGTCTAGTGATTGCTATGTATCTTCCA
ATTTTCCAAATGGGCTCAGTCATATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A022J0M4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

97.549

100

0.975
  pilC Acinetobacter baylyi ADP1

85.294

100

0.853
  pilC Pseudomonas stutzeri DSM 10701

59.259

99.265

0.588
  pilC Legionella pneumophila strain ERS1305867

52.84

99.265

0.525
  pilG Neisseria gonorrhoeae MS11

46.231

97.549

0.451
  pilG Neisseria meningitidis 44/76-A

46.231

97.549

0.451
  pilC Vibrio cholerae strain A1552

42.402

100

0.424
  pilC Vibrio campbellii strain DS40M4

40.098

100

0.402
  pilC Thermus thermophilus HB27

37.157

98.284

0.365

Multiple sequence alignment