Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   O1Q77_RS01935 Genome accession   NZ_CP114182
Coordinates   398424..399665 (-) Length   413 a.a.
NCBI ID   WP_005355091.1    Uniprot ID   A0A2T4MY12
Organism   Aeromonas veronii strain AS1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 393424..404665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O1Q77_RS01910 (O1Q77_01910) mutT 395416..395820 (+) 405 WP_019444787.1 8-oxo-dGTP diphosphatase MutT -
  O1Q77_RS01915 (O1Q77_01915) yacG 395898..396092 (-) 195 WP_069527075.1 DNA gyrase inhibitor YacG -
  O1Q77_RS01920 (O1Q77_01920) zapD 396102..396824 (-) 723 WP_005336141.1 cell division protein ZapD -
  O1Q77_RS01925 (O1Q77_01925) coaE 396868..397476 (-) 609 WP_304520465.1 dephospho-CoA kinase -
  O1Q77_RS01930 (O1Q77_01930) pilD 397490..398362 (-) 873 WP_304520466.1 A24 family peptidase Machinery gene
  O1Q77_RS01935 (O1Q77_01935) pilC 398424..399665 (-) 1242 WP_005355091.1 type II secretion system F family protein Machinery gene
  O1Q77_RS01940 (O1Q77_01940) pilB 399905..401611 (-) 1707 WP_005336134.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  O1Q77_RS01945 (O1Q77_01945) - 401616..402017 (-) 402 WP_120416063.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  O1Q77_RS01950 (O1Q77_01950) nadC 402333..403196 (-) 864 WP_279464204.1 carboxylating nicotinate-nucleotide diphosphorylase -
  O1Q77_RS01955 (O1Q77_01955) - 403200..403670 (-) 471 WP_040068932.1 TIGR02281 family clan AA aspartic protease -
  O1Q77_RS01960 (O1Q77_01960) ampD 403801..404376 (+) 576 WP_236280279.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45441.57 Da        Isoelectric Point: 9.7221

>NTDB_id=764832 O1Q77_RS01935 WP_005355091.1 398424..399665(-) (pilC) [Aeromonas veronii strain AS1]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGEVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=764832 O1Q77_RS01935 WP_005355091.1 398424..399665(-) (pilC) [Aeromonas veronii strain AS1]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTACAGGCCGACAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTGGCCAAAAAATCCCAAGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCACGC
CAAATAACTACCATGCTCTCCGCCGGTGTACCGCTGGTGCAAAGCCTGCAGATTATCGCCCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCGGAGGCGCTGCGCCGCCATCCCC
TCTACTTTGATGATCTCTATTGCGATCTTGTGGAAGCCGGTGAGCAATCCGGTGCGCTGGAGACCATCTACGACCGTATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAATCGAAGATCAAGAAGGCAATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATTGTGGTCACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACCGCC
CTTGGCATCTTCCTCTATGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCTCGCTTTGCCCGTACTCTTTCAACCACTTTCTCTGCCGGTA
TTCCGCTGGTAGATGCGCTGATTTCAGCAGCAGGGGCCTCCGGCAACTATGTCTATCGCACCGCCGTCATGGCGATCCGC
AACGAGGTGGTGGCAGGCATGCAGATCAACGTGGCAATGCGCACCGTCGATCTCTTTCCCGACATGGTGATCCAAATGGT
GATGATCGGTGAGGAGTCCGGAGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATTGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGAAGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4MY12

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368