Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PALA52_RS23255 Genome accession   NZ_CP110347
Coordinates   5042896..5044116 (+) Length   406 a.a.
NCBI ID   WP_024914667.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain PALA52     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5037896..5049116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PALA52_RS23235 (PALA52_04614) nadC 5039460..5040308 (+) 849 WP_058141272.1 carboxylating nicotinate-nucleotide diphosphorylase -
  PALA52_RS23245 pilA 5040510..5040959 (-) 450 WP_003112842.1 type 4a pilus biogenesis protein PilA Machinery gene
  PALA52_RS23250 (PALA52_04616) pilB 5041192..5042892 (+) 1701 WP_024914668.1 type IV-A pilus assembly ATPase PilB Machinery gene
  PALA52_RS23255 (PALA52_04617) pilC 5042896..5044116 (+) 1221 WP_024914667.1 type 4a pilus biogenesis protein PilC Machinery gene
  PALA52_RS23260 (PALA52_04618) pilD 5044120..5044992 (+) 873 WP_003125204.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  PALA52_RS23265 (PALA52_04619) coaE 5044989..5045600 (+) 612 WP_003094654.1 dephospho-CoA kinase -
  PALA52_RS23270 (PALA52_04620) yacG 5045597..5045797 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  PALA52_RS23275 (PALA52_04621) - 5045835..5046044 (-) 210 WP_003094660.1 hypothetical protein -
  PALA52_RS23280 (PALA52_04622) - 5046150..5046839 (-) 690 WP_058141274.1 energy-coupling factor ABC transporter permease -
  PALA52_RS23285 (PALA52_04623) - 5046836..5047306 (-) 471 WP_024914665.1 hypothetical protein -
  PALA52_RS23290 (PALA52_04624) - 5047303..5047728 (-) 426 WP_024914664.1 GNAT family N-acetyltransferase -
  PALA52_RS23295 (PALA52_04625) - 5047861..5048490 (+) 630 WP_024914663.1 DUF1780 domain-containing protein -
  PALA52_RS23300 (PALA52_04626) - 5048487..5048936 (+) 450 WP_024914662.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44346.12 Da        Isoelectric Point: 9.8784

>NTDB_id=754274 PALA52_RS23255 WP_024914667.1 5042896..5044116(+) (pilC) [Pseudomonas aeruginosa strain PALA52]
MADKALKTSVFIWEGTDKKGAKVKGELTGQNPMLVKAHLRKQGINPLKVRKKGISLLGAGKKVKPMDIALFTRQMATMMG
AGVPLLQSFDIIGEGFDNPNMRKLVDEIKQEVSSGNSLANSLRKKPQYFDELYCNLVDAGEQSGALENLLDRVATYKEKT
ESLKAKIRKAMTYPIAVIIVALIVSAILLIKVVPQFQSVFQGFGAELPAFTQMVVNLSEFLQEWWLAVIVGVGVIGFTFK
ELHKRSKKFRDALDRTILKLPIFGGIVYKSTVARYARTLSTTFAAGVPLVDALDSVSGATGNIVFKNAVSKIKQDVSTGM
QLNFSMRTTSVFPNMAIQMTAIGEESGSLDEMLSKVASYYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIVAMYLPIFQ
LGNVVG

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=754274 PALA52_RS23255 WP_024914667.1 5042896..5044116(+) (pilC) [Pseudomonas aeruginosa strain PALA52]
ATGGCGGACAAAGCGTTAAAAACCAGCGTATTCATCTGGGAGGGCACCGACAAGAAAGGCGCCAAGGTCAAGGGCGAACT
GACCGGGCAGAATCCCATGCTGGTGAAGGCCCATCTGCGCAAGCAAGGCATCAATCCGCTCAAGGTACGCAAGAAAGGTA
TCTCCCTGCTGGGCGCAGGCAAGAAAGTCAAACCAATGGACATCGCCCTGTTCACTCGGCAGATGGCGACCATGATGGGT
GCTGGCGTTCCCCTCCTGCAATCGTTCGACATCATCGGCGAAGGCTTCGACAATCCCAACATGCGCAAGCTGGTGGATGA
GATCAAGCAGGAAGTGTCCTCGGGCAACAGCCTGGCCAACTCACTGAGAAAGAAACCGCAGTACTTCGACGAACTCTATT
GCAACCTGGTCGATGCCGGCGAGCAATCGGGCGCCTTGGAAAACTTGCTGGATAGAGTCGCGACCTACAAGGAAAAAACG
GAATCGTTAAAAGCAAAGATCAGGAAGGCGATGACTTATCCTATCGCCGTCATCATCGTTGCCTTGATCGTCTCCGCCAT
TCTTCTGATCAAGGTCGTCCCGCAGTTCCAATCCGTATTCCAAGGTTTTGGCGCAGAGCTGCCTGCATTCACTCAAATGG
TCGTAAATTTATCCGAGTTCCTACAGGAGTGGTGGCTTGCCGTCATCGTTGGCGTGGGGGTGATTGGCTTTACCTTCAAG
GAACTGCATAAACGCTCGAAGAAATTCCGCGACGCACTCGACAGAACGATCCTCAAACTTCCCATTTTCGGAGGCATCGT
CTACAAATCCACGGTAGCCCGTTATGCACGGACCTTGTCCACGACCTTCGCCGCGGGTGTTCCCCTGGTCGATGCGCTCG
ACTCCGTCTCCGGAGCGACCGGTAATATCGTGTTCAAGAACGCGGTCAGCAAGATCAAGCAAGACGTTTCCACCGGCATG
CAGCTCAACTTCTCCATGCGCACCACCAGCGTCTTTCCCAACATGGCGATCCAGATGACCGCCATCGGCGAGGAGTCCGG
TTCGCTCGACGAGATGCTGAGCAAAGTCGCCAGCTACTACGAAGAGGAAGTCGACAACGCCGTGGACAACCTCACCACGC
TCATGGAACCGATGATCATGGCCGTTCTCGGCGTACTGGTTGGCGGTCTGATCGTGGCCATGTACCTTCCGATCTTCCAA
CTCGGCAACGTCGTCGGATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

77.037

99.754

0.768
  pilC Acinetobacter baumannii D1279779

60.644

99.507

0.603
  pilC Acinetobacter baylyi ADP1

60.345

100

0.603
  pilC Legionella pneumophila strain ERS1305867

54.04

97.537

0.527
  pilG Neisseria meningitidis 44/76-A

45.906

99.261

0.456
  pilG Neisseria gonorrhoeae MS11

45.658

99.261

0.453
  pilC Vibrio cholerae strain A1552

42.365

100

0.424
  pilC Vibrio campbellii strain DS40M4

41.353

98.276

0.406
  pilC Thermus thermophilus HB27

36.658

98.768

0.362