Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   UKS_RS08515 Genome accession   NZ_AP021887
Coordinates   1698612..1699868 (-) Length   418 a.a.
NCBI ID   WP_156012728.1    Uniprot ID   A0A6H3S7E3
Organism   Streptococcus sp. 116-D4     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1693612..1704868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS08490 (UKS_16440) - 1693971..1694687 (-) 717 WP_156012721.1 YebC/PmpR family DNA-binding transcriptional regulator -
  UKS_RS08495 (UKS_16450) - 1694784..1696154 (-) 1371 WP_156012723.1 MATE family efflux transporter -
  UKS_RS08500 (UKS_16460) - 1696276..1696830 (+) 555 WP_156012725.1 GNAT family N-acetyltransferase -
  UKS_RS09975 - 1697033..1697226 (-) 194 Protein_1628 PspC domain-containing protein -
  UKS_RS08510 (UKS_16470) recA 1697391..1698557 (-) 1167 WP_156012726.1 recombinase RecA Machinery gene
  UKS_RS08515 (UKS_16480) cinA 1698612..1699868 (-) 1257 WP_156012728.1 competence/damage-inducible protein A Machinery gene
  UKS_RS08520 (UKS_16490) - 1699957..1701009 (-) 1053 WP_156012730.1 LCP family protein -
  UKS_RS08525 (UKS_16500) - 1701017..1701535 (-) 519 WP_049496202.1 GNAT family N-acetyltransferase -
  UKS_RS08530 (UKS_16510) tsaE 1701525..1701968 (-) 444 WP_156012732.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  UKS_RS08535 (UKS_16520) comM 1702233..1702865 (-) 633 WP_232049741.1 competence protein Regulator
  UKS_RS08540 (UKS_16530) ndk 1702996..1703418 (-) 423 WP_049496208.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45073.42 Da        Isoelectric Point: 4.5700

>NTDB_id=75381 UKS_RS08515 WP_156012728.1 1698612..1699868(-) (cinA) [Streptococcus sp. 116-D4]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAQFLGKELVFDLQAQEKLDVFFAQRPDYARTPNNERQAQIVEGATPLPNETGLAVGGMLEVKGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKASNQEEANKGLDILENQI
LGRQTFEGLSLQDLCYGYGEETSIASIVVEELKKQGKTITAAESLTAGLFQATVADFPGASSIFKGGFVTYSLEEKSKML
DIPAKDLEEQGVVSEYTAQKMAEQARIKTQSDFGLSLTGVAGPDNLEGHPAGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=75381 UKS_RS08515 WP_156012728.1 1698612..1699868(-) (cinA) [Streptococcus sp. 116-D4]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACTAATGCTCAATTTTTATCGGA
AAAACTAGCTGAGATTGGAGTAGATGTTTATTTCCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGTGGTTTGGGACCAACTGAGGACGATTTGACCAAACAAACC
CTGGCTCAATTTTTAGGGAAAGAATTAGTCTTCGATCTTCAGGCGCAGGAGAAGTTGGATGTCTTTTTTGCCCAGAGACC
AGACTATGCCCGAACACCGAATAATGAAAGACAAGCTCAAATTGTAGAAGGGGCGACTCCACTGCCCAACGAAACGGGAC
TGGCTGTGGGAGGAATGTTAGAAGTCAAAGGAGTGACTTATGTCGTCCTTCCTGGTCCACCAAGTGAATTGAAACCGATG
GTCTTAAACCAGCTTCTACCCAAGTTGATGACAGGGAGTAAGCTATATTCCCGAGTTCTTCGTTTTTTTGGAATTGGCGA
GAGCCAGCTGGTGACGATTTTGGCTGATTTGATTGATCATCAAACAGATCCGACCTTGGCACCTTATGCCAAGACAGGAG
AGGTGACTCTACGTCTGTCAACAAAAGCTAGCAATCAAGAAGAGGCGAATAAAGGGCTGGATATCTTGGAAAATCAAATC
TTAGGTCGCCAAACTTTTGAAGGACTTTCTTTACAAGACCTTTGCTATGGTTATGGTGAAGAAACTAGTATAGCCAGCAT
TGTGGTAGAAGAACTGAAAAAACAGGGGAAAACCATCACGGCTGCAGAGAGCTTGACGGCAGGCCTTTTTCAAGCAACCG
TAGCGGATTTTCCGGGTGCTTCCAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAAGATGTTG
GATATTCCTGCCAAGGATTTGGAAGAACAGGGTGTGGTGTCTGAATATACAGCTCAGAAGATGGCTGAGCAGGCACGAAT
CAAGACCCAGTCTGATTTTGGCCTTAGTTTGACTGGAGTGGCAGGACCAGATAACTTAGAAGGACACCCAGCTGGAACAG
TCTTTATAGGCTTGGCTCAAGAGCAAGGAACTGAGGTCATCAAGGTTAATATTGGAGGTAGGAGTCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6H3S7E3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

95.215

100

0.952
  cinA Streptococcus mitis NCTC 12261

94.976

100

0.95
  cinA Streptococcus pneumoniae TIGR4

91.627

100

0.916
  cinA Streptococcus pneumoniae Rx1

91.388

100

0.914
  cinA Streptococcus pneumoniae R6

91.388

100

0.914
  cinA Streptococcus pneumoniae D39

91.148

100

0.911
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

54.567

99.522

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment