NTDB

Overview

Name	pilC	Type	Machinery gene
Locus tag	N2K12_RS02805	Genome accession	NZ_CP104279
Coordinates	598279..599502 (-)	Length	407 a.a.
NCBI ID	WP_045267485.1	Uniprot ID	A0A7X2I2Z9
Organism	Comamonas aquatica strain SCLZS63
Function	assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 593279..604502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N2K12_RS02775	-	594194..595126 (+)	933	WP_043379904.1	ATP-binding protein	-
N2K12_RS02780	-	595148..595609 (+)	462	WP_260674809.1	NUDIX domain-containing protein	-
N2K12_RS02785	-	595713..595922 (-)	210	WP_045267488.1	DNA gyrase inhibitor YacG	-
N2K12_RS02790	zapD	595949..596704 (-)	756	WP_042419933.1	cell division protein ZapD	-
N2K12_RS02795	coaE	596799..597407 (-)	609	WP_154163335.1	dephospho-CoA kinase	-
N2K12_RS02800	pilD	597410..598279 (-)	870	WP_260674810.1	A24 family peptidase	Machinery gene
N2K12_RS02805	pilC	598279..599502 (-)	1224	WP_045267485.1	type II secretion system F family protein	Machinery gene
N2K12_RS02810	pilB	599554..601299 (-)	1746	WP_210930174.1	type IV-A pilus assembly ATPase PilB	Machinery gene
N2K12_RS02815	-	601458..602387 (-)	930	WP_210931650.1	polyprenyl synthetase family protein	-
N2K12_RS02820	rplU	602598..602909 (+)	312	WP_042417032.1	50S ribosomal protein L21	-
N2K12_RS02825	rpmA	602928..603188 (+)	261	WP_042416998.1	50S ribosomal protein L27	-
N2K12_RS02830	cgtA	603352..604425 (+)	1074	WP_042416995.1	Obg family GTPase CgtA	-

Sequence

Protein

Download Length: 407 a.a. Molecular weight: 44589.73 Da Isoelectric Point: 9.5471

                                >NTDB_id=728205 N2K12_RS02805 WP_045267485.1 598279..599502(-) (pilC) [Comamonas aquatica strain SCLZS63]

MATAAPGRSNAKEFIYEWAGKDRQGKALHGEMRAVGEAQVQASLRRQGIFITKLKKRSMRAGKKIKPKDIALFTRQMATM

MKAGVPLLQSFDIVGRGNPNPSVTKLLNDIRQDVETGTSLSMAFRKHPMHFNALYCNLIEAGEAAGILDTLMDRLATYME

KTEAIKGKIKSALMYPIAVIVVAFVVVTVIMIFVIPAFKEVFTSFGADLPAPTLLVMAISEFFVAYWWLIFGVIGGGLYF

FMQAWRRSPKMQRVMDRLLLKLPIFGILIDKSCVARWTRTLSTMFAAGVPLVEALDSVGGASGNSVYREATDKIQQMVAT

GTNLTDAMTSADVFPSMVLQMCAIGEESGSIDHMLGKAADFYEQEVDEMVAGLSSLMEPIIIVILGGIIGGIVVSMYLPI

FKLGQVV

Nucleotide

Download Length: 1224 bp

                                >NTDB_id=728205 N2K12_RS02805 WP_045267485.1 598279..599502(-) (pilC) [Comamonas aquatica strain SCLZS63]

ATGGCAACCGCAGCACCTGGCAGGAGCAACGCAAAGGAGTTCATTTACGAATGGGCCGGCAAAGACCGCCAGGGCAAGGC

ACTGCACGGAGAGATGCGGGCCGTTGGGGAAGCCCAGGTCCAGGCCTCCTTGCGCCGCCAGGGCATCTTCATCACCAAGC

TGAAGAAGCGCAGCATGCGCGCCGGCAAGAAGATCAAGCCCAAGGACATTGCGCTGTTCACCCGCCAGATGGCCACCATG

ATGAAGGCCGGGGTCCCGCTGCTGCAGTCGTTCGACATCGTCGGGCGTGGCAACCCCAATCCCAGCGTGACCAAGCTGCT

CAACGACATCCGCCAGGATGTGGAGACCGGCACCTCGCTGAGCATGGCGTTCCGCAAGCACCCCATGCACTTCAACGCCT

TGTACTGCAACCTGATCGAGGCCGGGGAAGCTGCGGGCATCCTGGACACCTTGATGGACCGCCTGGCCACCTACATGGAA

AAGACCGAGGCCATCAAGGGCAAGATCAAGTCCGCGCTGATGTACCCCATCGCGGTGATCGTGGTGGCGTTCGTGGTGGT

GACGGTGATCATGATCTTTGTGATCCCGGCGTTCAAGGAAGTCTTCACCTCGTTCGGCGCCGACCTACCGGCCCCGACGC

TGCTGGTCATGGCCATCAGTGAGTTCTTTGTCGCATATTGGTGGCTGATCTTTGGCGTGATCGGTGGCGGCCTGTATTTC

TTCATGCAGGCCTGGCGGCGCAGTCCCAAAATGCAGCGCGTGATGGACCGGCTGCTGCTGAAGCTGCCCATTTTTGGCAT

CCTGATCGACAAATCCTGCGTCGCCCGCTGGACACGCACCCTCTCCACCATGTTCGCCGCCGGTGTGCCCCTGGTGGAAG

CACTGGACTCCGTCGGCGGCGCCTCGGGCAACAGCGTCTACCGGGAAGCCACCGACAAGATCCAGCAGATGGTTGCCACC

GGCACCAATCTCACCGATGCCATGACAAGTGCCGATGTCTTCCCGTCGATGGTGCTGCAGATGTGTGCCATCGGCGAGGA

ATCGGGCTCCATCGATCACATGCTGGGCAAGGCGGCCGACTTCTACGAACAGGAAGTGGACGAGATGGTCGCTGGCCTTT

CCAGCCTGATGGAGCCCATCATCATCGTGATCCTGGGTGGCATCATCGGCGGGATTGTGGTGTCCATGTACCTGCCGATC

TTCAAGTTAGGACAAGTGGTCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(73-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A7X2I2Z9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilC	Pseudomonas stutzeri DSM 10701	54.887	98.034	0.538
pilG	Neisseria gonorrhoeae MS11	51.01	97.297	0.496
pilG	Neisseria meningitidis 44/76-A	50.758	97.297	0.494
pilC	Legionella pneumophila strain ERS1305867	50.505	97.297	0.491
pilC	Acinetobacter baylyi ADP1	49.246	97.789	0.482
pilC	Acinetobacter baumannii D1279779	48.622	98.034	0.477
pilC	Vibrio campbellii strain DS40M4	40.049	100	0.405
pilC	Thermus thermophilus HB27	39.089	100	0.4
pilC	Vibrio cholerae strain A1552	40.909	97.297	0.398

Detailed information NTG0728205