Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NYS59_RS24405 Genome accession   NZ_CP103789
Coordinates   5238000..5239217 (+) Length   405 a.a.
NCBI ID   WP_003161763.1    Uniprot ID   A0A3P3S6C0
Organism   Pseudomonas aeruginosa strain 2718     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5233000..5244217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYS59_RS24375 nadC 5233102..5233950 (+) 849 WP_023435051.1 carboxylating nicotinate-nucleotide diphosphorylase -
  NYS59_RS24385 - 5234131..5235060 (-) 930 WP_240462250.1 O-antigen ligase family protein -
  NYS59_RS24390 - 5235106..5235513 (-) 408 WP_316927926.1 hypothetical protein -
  NYS59_RS24395 - 5235601..5236065 (-) 465 WP_058156624.1 pilin -
  NYS59_RS24400 pilB 5236296..5237996 (+) 1701 WP_033956582.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NYS59_RS24405 pilC 5238000..5239217 (+) 1218 WP_003161763.1 type II secretion system F family protein Machinery gene
  NYS59_RS24410 pilD 5239218..5240090 (+) 873 WP_128652216.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  NYS59_RS24415 coaE 5240087..5240698 (+) 612 WP_003094654.1 dephospho-CoA kinase -
  NYS59_RS24420 yacG 5240695..5240895 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  NYS59_RS24425 - 5240932..5241141 (-) 210 WP_003094660.1 hypothetical protein -
  NYS59_RS24430 - 5241247..5241936 (-) 690 WP_003103868.1 energy-coupling factor ABC transporter permease -
  NYS59_RS24435 - 5241933..5242403 (-) 471 WP_003094664.1 hypothetical protein -
  NYS59_RS24440 - 5242400..5242825 (-) 426 WP_003103865.1 GNAT family N-acetyltransferase -
  NYS59_RS24445 - 5242958..5243587 (+) 630 WP_003094668.1 DUF1780 domain-containing protein -
  NYS59_RS24450 - 5243584..5244033 (+) 450 WP_023126574.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43998.80 Da        Isoelectric Point: 9.8103

>NTDB_id=725081 NYS59_RS24405 WP_003161763.1 5238000..5239217(+) (pilC) [Pseudomonas aeruginosa strain 2718]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTQMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVGKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=725081 NYS59_RS24405 WP_003161763.1 5238000..5239217(+) (pilC) [Pseudomonas aeruginosa strain 2718]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TTTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATGGACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCCGGCGTGCCACTGCTGCAGTCATTCGACATCATCAGCGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGA
GATCAAGCAGGAAGTCGCCGGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACT
GCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTGGAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCGGCCTTCACCCAAATGG
TCATCAATATCTCCAACGTGCTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCGATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGGCAAGATCAAGCAGGACGTGTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTCCCCAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
CTGGGCAACGTCGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P3S6C0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baylyi ADP1

61.275

100

0.617
  pilC Acinetobacter baumannii D1279779

60.644

99.753

0.605
  pilC Legionella pneumophila strain ERS1305867

54.293

97.778

0.531
  pilG Neisseria gonorrhoeae MS11

46.287

99.753

0.462
  pilG Neisseria meningitidis 44/76-A

45.771

99.259

0.454
  pilC Vibrio cholerae strain A1552

41.728

100

0.417
  pilC Vibrio campbellii strain DS40M4

40.898

99.012

0.405
  pilC Thermus thermophilus HB27

38.155

99.012

0.378