Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EKM72_RS03520 Genome accession   NZ_AP019305
Coordinates   640960..641589 (-) Length   209 a.a.
NCBI ID   WP_042109421.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM9458     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 635960..646589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM72_RS03490 - 636380..636910 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  EKM72_RS03495 - 637000..638256 (-) 1257 WP_125571275.1 aminopeptidase -
  EKM72_RS03500 - 638259..638459 (-) 201 WP_000180460.1 DUF1128 family protein -
  EKM72_RS03505 - 638606..639070 (+) 465 WP_042109418.1 low molecular weight protein-tyrosine-phosphatase -
  EKM72_RS03510 - 639077..639352 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  EKM72_RS03515 - 639630..640847 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  EKM72_RS03520 vraR 640960..641589 (-) 630 WP_042109421.1 two-component system response regulator VraR Regulator
  EKM72_RS03525 vraS 641579..642622 (-) 1044 WP_125571277.1 sensor histidine kinase Regulator
  EKM72_RS03530 liaF 642619..643320 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  EKM72_RS03535 - 643335..643721 (-) 387 WP_001110179.1 hypothetical protein -
  EKM72_RS03540 map 643938..644696 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  EKM72_RS03550 - 645227..646213 (+) 987 WP_000999717.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23569.36 Da        Isoelectric Point: 5.3935

>NTDB_id=72260 EKM72_RS03520 WP_042109421.1 640960..641589(-) (vraR) [Staphylococcus aureus strain TUM9458]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYPNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=72260 EKM72_RS03520 WP_042109421.1 640960..641589(-) (vraR) [Staphylococcus aureus strain TUM9458]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACCCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment