Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   EL334_RS10570 Genome accession   NZ_AP019192
Coordinates   1937559..1938500 (-) Length   313 a.a.
NCBI ID   WP_126432103.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ASP0581     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1932559..1943500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL334_RS10530 (ASP0581_19540) comYH 1933052..1934005 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  EL334_RS10535 (ASP0581_19550) - 1934066..1934653 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  EL334_RS10540 (ASP0581_19560) comGG/cglG 1934790..1935203 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL334_RS10545 comGF/cglF 1935181..1935642 (-) 462 WP_033705217.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL334_RS10550 (ASP0581_19580) comGE/cglE 1935605..1935907 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL334_RS10555 (ASP0581_19590) comGD/cglD 1935870..1936274 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL334_RS10560 (ASP0581_19600) comGC/cglC 1936267..1936593 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  EL334_RS10565 (ASP0581_19610) comGB/cglB 1936595..1937611 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL334_RS10570 (ASP0581_19620) comGA/cglA/cilD 1937559..1938500 (-) 942 WP_126432103.1 competence type IV pilus ATPase ComGA Machinery gene
  EL334_RS10575 (ASP0581_19630) - 1938576..1938941 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL334_RS10580 (ASP0581_19640) - 1939092..1940150 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EL334_RS10585 (ASP0581_19650) nagA 1940313..1941464 (-) 1152 WP_033705218.1 N-acetylglucosamine-6-phosphate deacetylase -
  EL334_RS10590 (ASP0581_19660) - 1941617..1943434 (-) 1818 WP_001220843.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35564.49 Da        Isoelectric Point: 6.0083

>NTDB_id=72173 EL334_RS10570 WP_126432103.1 1937559..1938500(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain ASP0581]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFTSRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=72173 EL334_RS10570 WP_126432103.1 1937559..1938500(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain ASP0581]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAAAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTACAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

41.877

88.498

0.371

Multiple sequence alignment