Detailed information NTG0720723

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NW955_RS09555
• Genome accession: NZ_CP102966
• Coordinates: 1945539..1946582 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 29-P-01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1940539..1951582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW955_RS09525 (NW955_09525)	-	1940960..1942216 (-)	1257	WP_001793428.1	aminopeptidase	-
NW955_RS09530 (NW955_09530)	-	1942219..1942419 (-)	201	WP_000180460.1	DUF1128 family protein	-
NW955_RS09535 (NW955_09535)	-	1942566..1943030 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NW955_RS09540 (NW955_09540)	-	1943037..1943312 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NW955_RS09545 (NW955_09545)	-	1943590..1944807 (+)	1218	WP_045158466.1	YihY/virulence factor BrkB family protein	-
NW955_RS09550 (NW955_09550)	vraR	1944920..1945549 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
NW955_RS09555 (NW955_09555)	vraS	1945539..1946582 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NW955_RS09560 (NW955_09560)	liaF	1946579..1947280 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
NW955_RS09565 (NW955_09565)	-	1947295..1947681 (-)	387	WP_001110179.1	hypothetical protein	-
NW955_RS09570 (NW955_09570)	map	1947898..1948656 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NW955_RS09575 (NW955_09575)	-	1949183..1950169 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
NW955_RS09580 (NW955_09580)	-	1950358..1950771 (-)	414	WP_258412606.1	hypothetical protein	-
NW955_RS09585 (NW955_09585)	-	1950800..1950908 (-)	109	Protein_1848	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=720723 NW955_RS09555 WP_001017131.1 1945539..1946582(-) (vraS) [Staphylococcus aureus strain 29-P-01]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=720723 NW955_RS09555 WP_001017131.1 1945539..1946582(-) (vraS) [Staphylococcus aureus strain 29-P-01]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTACTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTGCAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1