Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NW955_RS09950 Genome accession   NZ_CP102966
Coordinates   2023114..2023830 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 29-P-01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2018114..2028830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW955_RS09920 (NW955_09920) - 2018333..2018959 (+) 627 Protein_1914 nitroreductase family protein -
  NW955_RS09925 (NW955_09925) - 2019320..2020105 (+) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  NW955_RS09930 (NW955_09930) - 2020702..2020836 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NW955_RS09935 (NW955_09935) agrB 2021072..2021641 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  NW955_RS09940 (NW955_09940) agrD 2021638..2021778 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NW955_RS09945 (NW955_09945) agrC 2021803..2023095 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  NW955_RS09950 (NW955_09950) agrA 2023114..2023830 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NW955_RS09955 (NW955_09955) - 2023910..2024019 (+) 110 Protein_1921 hypothetical protein -
  NW955_RS09960 (NW955_09960) - 2024207..2025166 (-) 960 WP_001253302.1 carbohydrate kinase -
  NW955_RS09965 (NW955_09965) - 2025163..2026647 (-) 1485 WP_258411747.1 sucrose-6-phosphate hydrolase -
  NW955_RS09970 (NW955_09970) - 2026796..2027746 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=720724 NW955_RS09950 WP_000688498.1 2023114..2023830(+) (agrA) [Staphylococcus aureus strain 29-P-01]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=720724 NW955_RS09950 WP_000688498.1 2023114..2023830(+) (agrA) [Staphylococcus aureus strain 29-P-01]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996