Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   MOP79_RS09195 Genome accession   NZ_CP102583
Coordinates   1811094..1812035 (+) Length   313 a.a.
NCBI ID   WP_000249564.1    Uniprot ID   Q8DN86
Organism   Streptococcus pneumoniae strain D39Mega17545     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1806094..1817035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOP79_RS09175 - 1806160..1807977 (+) 1818 WP_001220853.1 acyltransferase family protein -
  MOP79_RS09180 nagA 1808130..1809281 (+) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  MOP79_RS09185 - 1809444..1810502 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  MOP79_RS09190 - 1810653..1811018 (+) 366 WP_000286412.1 DUF1033 family protein -
  MOP79_RS09195 comGA/cglA/cilD 1811094..1812035 (+) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  MOP79_RS09200 comGB/cglB 1811983..1812999 (+) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  MOP79_RS09205 comGC/cglC 1813001..1813327 (+) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  MOP79_RS09210 comGD/cglD 1813320..1813724 (+) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  MOP79_RS09215 comGE/cglE 1813687..1813989 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  MOP79_RS09220 comGF/cglF 1813952..1814413 (+) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  MOP79_RS09225 comGG/cglG 1814391..1814804 (+) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  MOP79_RS09230 - 1814941..1815535 (+) 595 Protein_1830 class I SAM-dependent methyltransferase -
  MOP79_RS09235 comYH 1815596..1816549 (+) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35555.47 Da        Isoelectric Point: 6.1330

>NTDB_id=717890 MOP79_RS09195 WP_000249564.1 1811094..1812035(+) (comGA/cglA/cilD) [Streptococcus pneumoniae strain D39Mega17545]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDHKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=717890 MOP79_RS09195 WP_000249564.1 1811094..1812035(+) (comGA/cglA/cilD) [Streptococcus pneumoniae strain D39Mega17545]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATCTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCATAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DN86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.