Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   NUU05_RS01635 Genome accession   NZ_CP102538
Coordinates   294015..294956 (+) Length   313 a.a.
NCBI ID   WP_011681689.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TH-4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 289015..299956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUU05_RS01625 (NUU05_01615) rpoC 289775..293413 (+) 3639 WP_011681690.1 DNA-directed RNA polymerase subunit beta' -
  NUU05_RS01630 (NUU05_01620) - 293572..293934 (+) 363 WP_011226630.1 DUF1033 family protein -
  NUU05_RS01635 (NUU05_01625) comGA/cglA/cilD 294015..294956 (+) 942 WP_011681689.1 competence type IV pilus ATPase ComGA Machinery gene
  NUU05_RS01640 (NUU05_01630) comYB 294838..295938 (+) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  NUU05_RS01645 (NUU05_01635) comYC 295935..296261 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  NUU05_RS01650 (NUU05_01640) comYD 296221..296649 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  NUU05_RS01655 (NUU05_01645) comGE 296621..296914 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  NUU05_RS01660 (NUU05_01650) comYF 296898..297335 (+) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  NUU05_RS01665 (NUU05_01655) comGG 297313..297630 (+) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  NUU05_RS01670 (NUU05_01660) comYH 297675..298631 (+) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  NUU05_RS01675 (NUU05_01665) - 298687..299880 (+) 1194 WP_014608740.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35455.64 Da        Isoelectric Point: 6.3927

>NTDB_id=717606 NUU05_RS01635 WP_011681689.1 294015..294956(+) (comGA/cglA/cilD) [Streptococcus thermophilus strain TH-4]
MVTEFAKEMIKNADSCGAQDIYVFPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=717606 NUU05_RS01635 WP_011681689.1 294015..294956(+) (comGA/cglA/cilD) [Streptococcus thermophilus strain TH-4]
ATGGTAACAGAATTTGCTAAGGAAATGATAAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCTTTCCACGTCA
GGATAATTATGAGCTTTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comYA Streptococcus mutans UA159

64.217

100

0.642
  comYA Streptococcus mutans UA140

64.217

100

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377