Detailed information NTG0717607

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: NUU05_RS01640
• Genome accession: NZ_CP102538
• Coordinates: 294838..295938 (+)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TH-4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 289838..300938

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS01630 (NUU05_01620)	-	293572..293934 (+)	363	WP_011226630.1	DUF1033 family protein	-
NUU05_RS01635 (NUU05_01625)	comGA/cglA/cilD	294015..294956 (+)	942	WP_011681689.1	competence type IV pilus ATPase ComGA	Machinery gene
NUU05_RS01640 (NUU05_01630)	comYB	294838..295938 (+)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
NUU05_RS01645 (NUU05_01635)	comYC	295935..296261 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
NUU05_RS01650 (NUU05_01640)	comYD	296221..296649 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
NUU05_RS01655 (NUU05_01645)	comGE	296621..296914 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
NUU05_RS01660 (NUU05_01650)	comYF	296898..297335 (+)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
NUU05_RS01665 (NUU05_01655)	comGG	297313..297630 (+)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
NUU05_RS01670 (NUU05_01660)	comYH	297675..298631 (+)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
NUU05_RS01675 (NUU05_01665)	-	298687..299880 (+)	1194	WP_014608740.1	acetate kinase	-
NUU05_RS01680 (NUU05_01670)	-	300129..300326 (+)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
NUU05_RS01685 (NUU05_01675)	-	300338..300613 (+)	276	WP_011681681.1	hypothetical protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=717607 NUU05_RS01640 WP_120764773.1 294838..295938(+) (comYB) [Streptococcus thermophilus strain TH-4]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=717607 NUU05_RS01640 WP_120764773.1 294838..295938(+) (comYB) [Streptococcus thermophilus strain TH-4]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTCATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413