Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NRK99_RS19975 Genome accession   NZ_CP102326
Coordinates   4349843..4351084 (+) Length   413 a.a.
NCBI ID   WP_005305649.1    Uniprot ID   K1JJY1
Organism   Aeromonas dhakensis strain BC04     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4344843..4356084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NRK99_RS19950 (NRK99_19950) ampD 4345239..4345811 (-) 573 WP_126880607.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  NRK99_RS19955 (NRK99_19955) - 4345935..4346405 (+) 471 WP_010635963.1 TIGR02281 family clan AA aspartic protease -
  NRK99_RS19960 (NRK99_19960) nadC 4346410..4347267 (+) 858 WP_010635962.1 carboxylating nicotinate-nucleotide diphosphorylase -
  NRK99_RS19965 (NRK99_19965) tapA 4347589..4348017 (+) 429 WP_081304776.1 type IVa pilus major pilin TapA -
  NRK99_RS19970 (NRK99_19970) pilB 4348021..4349727 (+) 1707 WP_017766420.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  NRK99_RS19975 (NRK99_19975) pilC 4349843..4351084 (+) 1242 WP_005305649.1 type II secretion system F family protein Machinery gene
  NRK99_RS19980 (NRK99_19980) pilD 4351107..4351979 (+) 873 WP_268000069.1 prepilin peptidase Machinery gene
  NRK99_RS19985 (NRK99_19985) coaE 4351999..4352613 (+) 615 WP_126880609.1 dephospho-CoA kinase -
  NRK99_RS19990 (NRK99_19990) zapD 4352651..4353373 (+) 723 WP_026141277.1 cell division protein ZapD -
  NRK99_RS19995 (NRK99_19995) yacG 4353383..4353577 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  NRK99_RS20000 (NRK99_20000) mutT 4353638..4354051 (-) 414 WP_010635956.1 8-oxo-dGTP diphosphatase MutT -
  NRK99_RS20005 (NRK99_20005) - 4354060..4355238 (-) 1179 WP_126880610.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45440.57 Da        Isoelectric Point: 9.8734

>NTDB_id=716148 NRK99_RS19975 WP_005305649.1 4349843..4351084(+) (pilC) [Aeromonas dhakensis strain BC04]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQNWWYMIFGGVA
LAIFLYVRAWRASQKVRDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=716148 NRK99_RS19975 WP_005305649.1 4349843..4351084(+) (pilC) [Aeromonas dhakensis strain BC04]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAACCGCAAGGGCCA
GAAGGTCTCCGGCGAGCTGCAGGCCGACAGCATCAACACGGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATTGCCGTTGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAAGCGGC
CATGCGCGAGCTGATGGGTCAGATAGCCGCCGATGTGGAGACCGGTACCCCCATGTCCGAGGCGCTGCGCCGCCATCCCC
GCCACTTCGATGATCTCTATTGCGACCTGGTCGAGGCGGGCGAGCAGTCCGGCGCCCTGGAGACCATCTACGACCGCATC
GCGACTTATCGCGAAAAGTCCGAAGCGCTCAAATCCAAGATCAAGAAGGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTCACCTCCATTCTGCTGCTGTTCGTCATTCCGCAGTTTGAGGACATCTTCAAGAGCTTCGGCGCCGAAC
TGCCCGCCTTTACCCAGTTCGTCATCGGCATCTCCCGCTTCATGCAGAACTGGTGGTATATGATCTTTGGCGGGGTTGCA
CTCGCCATCTTCCTCTACGTGCGAGCCTGGCGTGCCTCGCAGAAAGTCAGAGACAACACCGACAAGTTCATTCTGACCAT
CCCGGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACCACCTTTTCTGCCGGTA
TCCCGCTGGTGGATGCCCTGATCTCCGCCGCAGGCGCCTCCGGCAACTATGTCTATCGCACCGCCGTCATGGCCATTCGC
AACGAGGTGGTAGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTGGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATTGGCGAGGAGTCAGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGAGTACTGGTCGGCGGCATGGTGGTCGCC
ATGTACCTGCCCATCTTCAAACTGGGGTCGGTCATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K1JJY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.576

95.884

0.552
  pilC Acinetobacter baumannii D1279779

54.25

96.852

0.525
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Vibrio cholerae strain A1552

47.99

96.368

0.462
  pilC Vibrio campbellii strain DS40M4

47.355

96.126

0.455
  pilG Neisseria meningitidis 44/76-A

40.494

98.063

0.397
  pilG Neisseria gonorrhoeae MS11

40.494

98.063

0.397
  pilC Thermus thermophilus HB27

38

96.852

0.368