Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EP379_RS11050 Genome accession   NZ_AP018724
Coordinates   2180603..2181823 (+) Length   406 a.a.
NCBI ID   WP_127477862.1    Uniprot ID   -
Organism   Sulfurivermis fontis strain JG42     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2175603..2186823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP379_RS11025 - 2176679..2176906 (+) 228 WP_127477858.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  EP379_RS11030 - 2176896..2177336 (+) 441 WP_127477859.1 type II toxin-antitoxin system VapC family toxin -
  EP379_RS11035 pilA 2177718..2178146 (+) 429 WP_127477860.1 pilin Machinery gene
  EP379_RS11040 - 2178276..2178707 (+) 432 WP_127477861.1 pilin -
  EP379_RS11045 pilB 2178885..2180600 (+) 1716 WP_172600452.1 type IV-A pilus assembly ATPase PilB Machinery gene
  EP379_RS11050 pilC 2180603..2181823 (+) 1221 WP_127477862.1 type II secretion system F family protein Machinery gene
  EP379_RS11055 pilD 2181837..2182709 (+) 873 WP_197722776.1 prepilin peptidase Machinery gene
  EP379_RS11060 coaE 2182713..2183312 (+) 600 WP_127477863.1 dephospho-CoA kinase -
  EP379_RS11065 zapD 2183343..2184110 (+) 768 WP_127477864.1 cell division protein ZapD -
  EP379_RS11070 yacG 2184107..2184307 (+) 201 WP_127477865.1 DNA gyrase inhibitor YacG -
  EP379_RS11075 - 2184319..2185266 (-) 948 WP_127477866.1 Nudix family hydrolase -
  EP379_RS11080 argJ 2185263..2186477 (-) 1215 WP_127477867.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 43615.32 Da        Isoelectric Point: 9.5056

>NTDB_id=70522 EP379_RS11050 WP_127477862.1 2180603..2181823(+) (pilC) [Sulfurivermis fontis strain JG42]
MAEKAPAQATFLWEGTDKRGARAKGEIQSSNAAQAKAELRRQGINPLKVKAKPKPLFGGRGKAITPKDIAIFTRQLATML
SSGVPLVQAFDIIGRGHEKASMRDLVLAIKADVEGGIALAEALRKHPAYFDSLTCNLVHAGEQAGILDSLLDKIATYKEK
TEAIKGKIKKAMFYPTAVIIAAFIITAILLIFVIPQFKEMFTSFGAELPALTLMVMAMSDYFVSYWWAIFGGLGAFIYGF
SQLKKRSKVFSEALQRLSLTFPVIGAILTKASIARFARTLSTMFAAGVPLVEAMDSVAGAVGNVVYSTAVTKMRDEVSTG
QSLQAAMTQSGVFPNMVCQMVAIGEEAGSIDTMLAKVADFYEEEVDNAVDGLSSLLEPLIMAFLGAVIGGLVIAMYLPIF
KMGQVV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=70522 EP379_RS11050 WP_127477862.1 2180603..2181823(+) (pilC) [Sulfurivermis fontis strain JG42]
ATGGCGGAAAAAGCTCCAGCACAAGCCACATTCCTGTGGGAAGGGACGGACAAGCGCGGCGCCCGCGCCAAGGGCGAGAT
CCAGTCCAGCAACGCTGCCCAGGCCAAGGCCGAGCTGCGGCGGCAAGGCATCAATCCCCTCAAGGTGAAGGCCAAGCCAA
AACCCCTGTTCGGCGGCCGCGGCAAGGCGATCACCCCGAAGGACATCGCCATCTTCACCCGCCAGCTGGCCACCATGCTG
TCCTCCGGTGTACCTCTGGTACAGGCCTTCGATATTATCGGCCGCGGCCATGAAAAGGCATCCATGCGCGACCTTGTCCT
GGCCATCAAGGCAGATGTCGAAGGCGGTATCGCCCTGGCCGAAGCATTGCGCAAACACCCAGCTTACTTCGATTCCCTCA
CCTGCAACCTGGTTCATGCCGGTGAACAGGCCGGTATCCTCGACTCGCTGCTGGACAAAATCGCTACGTACAAGGAAAAG
ACCGAGGCCATCAAAGGCAAGATCAAGAAGGCGATGTTTTATCCCACCGCGGTCATCATCGCGGCGTTTATCATTACCGC
CATCCTGCTGATTTTCGTCATCCCGCAGTTCAAGGAAATGTTTACCAGTTTTGGCGCGGAACTCCCCGCCCTGACCCTGA
TGGTCATGGCGATGTCTGATTATTTCGTGTCGTATTGGTGGGCTATCTTCGGCGGATTGGGCGCCTTCATTTACGGCTTC
AGCCAGTTGAAAAAACGTTCCAAGGTATTTTCTGAAGCACTACAGCGGCTGTCACTCACGTTTCCCGTCATTGGCGCCAT
CCTGACCAAGGCCTCCATTGCCCGTTTCGCGCGCACCCTGTCTACGATGTTTGCGGCCGGTGTGCCGCTCGTCGAGGCCA
TGGACTCTGTCGCTGGTGCCGTAGGCAATGTGGTGTACAGTACCGCCGTCACCAAAATGCGTGATGAGGTTTCCACTGGC
CAATCCCTGCAGGCCGCCATGACCCAGTCCGGCGTGTTTCCCAATATGGTGTGCCAGATGGTGGCGATCGGTGAGGAGGC
TGGTTCCATCGACACCATGCTGGCCAAGGTGGCCGACTTTTATGAGGAGGAGGTCGACAATGCCGTGGATGGCCTGAGCA
GCCTGCTGGAACCGCTGATCATGGCCTTCCTGGGCGCGGTCATTGGCGGCCTGGTAATTGCGATGTATCTGCCCATCTTC
AAGATGGGTCAGGTCGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.143

100

0.571
  pilC Legionella pneumophila strain ERS1305867

56.897

100

0.569
  pilC Acinetobacter baylyi ADP1

54.926

100

0.549
  pilC Acinetobacter baumannii D1279779

54.074

99.754

0.539
  pilG Neisseria gonorrhoeae MS11

47.291

100

0.473
  pilG Neisseria meningitidis 44/76-A

47.291

100

0.473
  pilC Vibrio cholerae strain A1552

42.065

97.783

0.411
  pilC Vibrio campbellii strain DS40M4

39.461

100

0.397
  pilC Thermus thermophilus HB27

38.313

100

0.392

Multiple sequence alignment