Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   MN084_RS12480 Genome accession   NZ_CP099567
Coordinates   2260892..2262127 (+) Length   411 a.a.
NCBI ID   WP_241086175.1    Uniprot ID   -
Organism   Candidatus Vondammii sp. HM_W22     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2255892..2267127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MN084_RS12455 - 2257324..2257515 (-) 192 WP_241086179.1 hypothetical protein -
  MN084_RS12460 - 2257815..2257967 (-) 153 WP_241086178.1 hypothetical protein -
  MN084_RS12465 - 2258066..2258545 (-) 480 WP_241086177.1 pilin -
  MN084_RS12470 - 2258765..2258895 (-) 131 Protein_2455 transposase -
  MN084_RS12475 pilB 2259174..2260886 (+) 1713 WP_241086176.1 type IV-A pilus assembly ATPase PilB Machinery gene
  MN084_RS12480 pilC 2260892..2262127 (+) 1236 WP_241086175.1 type II secretion system F family protein Machinery gene
  MN084_RS12485 pilD 2262218..2263090 (+) 873 WP_241086174.1 A24 family peptidase Machinery gene
  MN084_RS12490 coaE 2263096..2263695 (+) 600 WP_241086173.1 dephospho-CoA kinase -
  MN084_RS12495 zapD 2264179..2264475 (+) 297 WP_330178081.1 cell division protein ZapD -
  MN084_RS12500 - 2264634..2264834 (+) 201 WP_241086172.1 DNA gyrase inhibitor YacG -
  MN084_RS12505 - 2264902..2265843 (-) 942 WP_241086171.1 Nudix family hydrolase -
  MN084_RS12510 argJ 2265853..2267061 (-) 1209 WP_241086170.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 44591.79 Da        Isoelectric Point: 10.1528

>NTDB_id=700709 MN084_RS12480 WP_241086175.1 2260892..2262127(+) (pilC) [Candidatus Vondammii sp. HM_W22]
MAATAIAQKKVEKTKVFVWEGSDKKGKRVKGETRAPNIALVRAELRKQGIAPLKVKKKAASLFSTKKRITPRDIAVFSRQ
LATMMDAGIPLVQSFDIVGRGHEKPAMRDLLLAIKADIEGGTALAEALVKHPLYFDDLFCNLVRAGEAAGALETLLDKIA
SYKEMTESLKGKIKKALFYPVSVVIVAIVVTAIIMIFVIPQFQSIFSSFGGDLPAFTKAIVAASEWVQSYWWAVVLAVIG
SIYAFSYVFKRSRKLRQATDRMLLGTPVIGTILHKASIARFSRTLATMFAAGVPLVEALEAVAGATGNIIYGDAVMRMRE
DVATGQSLHLAMAQQKNFPHMVIQMVAIGEESGSLDHMLGKAADFFEEEVSNAVDALSSLLEPLIMVVIGTLVGALVIAM
YLPIFKMASVV

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=700709 MN084_RS12480 WP_241086175.1 2260892..2262127(+) (pilC) [Candidatus Vondammii sp. HM_W22]
ATGGCTGCCACTGCAATTGCTCAGAAAAAGGTTGAAAAAACCAAAGTATTTGTCTGGGAAGGATCGGATAAAAAAGGAAA
ACGGGTCAAAGGTGAAACCCGGGCACCCAACATTGCTTTGGTCAGAGCGGAACTGAGAAAACAGGGTATTGCGCCTTTGA
AAGTGAAAAAGAAAGCCGCTTCACTGTTCAGCACCAAAAAGCGAATCACGCCGAGAGATATCGCTGTCTTCAGCCGGCAA
CTTGCTACCATGATGGATGCAGGTATCCCCCTCGTTCAATCCTTCGATATAGTAGGGCGTGGCCATGAAAAACCGGCAAT
GCGAGATCTGCTGCTGGCCATCAAAGCCGATATTGAAGGAGGTACCGCATTAGCAGAAGCACTCGTCAAGCACCCGCTCT
ACTTCGACGATCTCTTCTGTAATCTGGTTCGTGCAGGTGAAGCGGCGGGTGCTCTTGAGACACTCCTTGATAAAATTGCC
AGCTATAAAGAGATGACCGAATCGCTGAAAGGAAAAATAAAGAAGGCATTATTCTATCCCGTTTCAGTTGTTATCGTGGC
AATTGTCGTCACCGCAATAATAATGATTTTCGTCATCCCACAATTCCAGAGCATTTTTTCAAGTTTTGGAGGGGATCTTC
CGGCATTCACAAAGGCCATTGTTGCTGCATCTGAATGGGTGCAATCTTACTGGTGGGCTGTTGTCTTGGCAGTTATCGGG
TCAATTTACGCTTTCTCCTACGTATTCAAACGATCACGTAAACTCAGGCAAGCAACAGACAGAATGCTTCTAGGGACACC
CGTTATCGGCACTATTCTCCACAAAGCATCGATCGCTCGTTTTTCCAGGACCCTGGCAACTATGTTTGCTGCAGGCGTTC
CTCTTGTCGAAGCGCTTGAAGCTGTTGCCGGTGCAACCGGTAATATCATCTATGGTGATGCCGTGATGCGTATGCGTGAG
GATGTCGCCACCGGTCAATCACTTCATCTCGCAATGGCGCAGCAAAAAAACTTTCCACACATGGTGATCCAGATGGTTGC
CATTGGTGAGGAATCCGGTTCCCTTGATCACATGCTGGGAAAGGCTGCGGACTTCTTCGAAGAGGAGGTAAGCAATGCTG
TAGATGCACTCAGCAGTCTGCTTGAACCGCTTATCATGGTGGTCATTGGCACCCTGGTGGGTGCACTCGTAATTGCGATG
TATCTCCCTATCTTCAAAATGGCATCCGTGGTCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(281-403)

Type II secretion system (T2SS), protein F (T2SSF)

(77-200)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

57.828

96.35

0.557
  pilC Acinetobacter baumannii D1279779

55.637

99.27

0.552
  pilC Pseudomonas stutzeri DSM 10701

55.172

98.783

0.545
  pilC Acinetobacter baylyi ADP1

54.412

99.27

0.54
  pilG Neisseria meningitidis 44/76-A

46.384

97.567

0.453
  pilG Neisseria gonorrhoeae MS11

46.384

97.567

0.453
  pilC Vibrio cholerae strain A1552

42.965

96.837

0.416
  pilC Vibrio campbellii strain DS40M4

40.602

97.08

0.394
  pilC Thermus thermophilus HB27

37.25

97.324

0.363