Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   M9H69_RS10320 Genome accession   NZ_CP097843
Coordinates   2059859..2059984 (-) Length   41 a.a.
NCBI ID   WP_195215739.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 2054859..2064984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS10295 (M9H69_10295) - 2056988..2057530 (+) 543 WP_000665086.1 TetR/AcrR family transcriptional regulator -
  M9H69_RS10310 (M9H69_10310) comE 2057770..2058522 (-) 753 WP_250315577.1 competence system response regulator transcription factor ComE Regulator
  M9H69_RS10315 (M9H69_10315) comD 2058519..2059838 (-) 1320 WP_250315578.1 competence system sensor histidine kinase ComD Regulator
  M9H69_RS10320 (M9H69_10320) comC/comC2 2059859..2059984 (-) 126 WP_195215739.1 competence-stimulating peptide ComC Regulator
  M9H69_RS10330 (M9H69_10330) rlmH 2060266..2060745 (-) 480 WP_250315579.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  M9H69_RS10335 (M9H69_10335) htrA 2060930..2062120 (+) 1191 WP_084911880.1 S1C family serine protease Regulator
  M9H69_RS10340 (M9H69_10340) spo0J 2062178..2062936 (+) 759 WP_250315580.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4959.79 Da        Isoelectric Point: 10.9293

>NTDB_id=692963 M9H69_RS10320 WP_195215739.1 2059859..2059984(-) (comC/comC2) [Streptococcus oralis strain HP01]
MKNTVKLEQFKEVTEAELQKIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=692963 M9H69_RS10320 WP_195215739.1 2059859..2059984(-) (comC/comC2) [Streptococcus oralis strain HP01]
ATGAAAAATACAGTAAAGTTGGAACAATTTAAAGAAGTAACAGAGGCAGAATTGCAGAAGATTCGGGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

58.537

100

0.585
  comC/comC2 Streptococcus pneumoniae TIGR4

58.537

100

0.585
  comC/comC1 Streptococcus pneumoniae R6

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae G54

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae D39

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae Rx1

56.098

100

0.561
  comC Streptococcus mitis SK321

53.659

100

0.537
  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463
  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39
  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366