Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   M9H69_RS10315 Genome accession   NZ_CP097843
Coordinates   2058519..2059838 (-) Length   439 a.a.
NCBI ID   WP_250315578.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2053519..2064838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS10290 (M9H69_10290) - 2054206..2056860 (-) 2655 WP_250315576.1 YhgE/Pip domain-containing protein -
  M9H69_RS10295 (M9H69_10295) - 2056988..2057530 (+) 543 WP_000665086.1 TetR/AcrR family transcriptional regulator -
  M9H69_RS10310 (M9H69_10310) comE 2057770..2058522 (-) 753 WP_250315577.1 competence system response regulator transcription factor ComE Regulator
  M9H69_RS10315 (M9H69_10315) comD 2058519..2059838 (-) 1320 WP_250315578.1 competence system sensor histidine kinase ComD Regulator
  M9H69_RS10320 (M9H69_10320) comC/comC2 2059859..2059984 (-) 126 WP_195215739.1 competence-stimulating peptide ComC Regulator
  M9H69_RS10330 (M9H69_10330) rlmH 2060266..2060745 (-) 480 WP_250315579.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  M9H69_RS10335 (M9H69_10335) htrA 2060930..2062120 (+) 1191 WP_084911880.1 S1C family serine protease Regulator
  M9H69_RS10340 (M9H69_10340) spo0J 2062178..2062936 (+) 759 WP_250315580.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51154.16 Da        Isoelectric Point: 6.9577

>NTDB_id=692962 M9H69_RS10315 WP_250315578.1 2058519..2059838(-) (comD) [Streptococcus oralis strain HP01]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSITGDEVVLHYKSTFLLVVLLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQVEKEIALKQKKFEQKYLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIADSALRSLIAQSIVYARNNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKLMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=692962 M9H69_RS10315 WP_250315578.1 2058519..2059838(-) (comD) [Streptococcus oralis strain HP01]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTACTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACCTTATCTTC
TATAACAGGAGATGAAGTAGTATTGCATTATAAAAGTACATTTCTTTTAGTAGTATTGTTGATGACTTATTTTTCTATTC
TAATAATAATTCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTGCATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCATAAGGTTCAAGTTGAAAAAG
AGATTGCTTTGAAGCAGAAAAAATTTGAACAAAAATATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGGATGCTTGTCAGCATGCAAATGGCGATTGACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCCTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAACA
ATATAGCAGATTCTGCCTTACGAAGTTTGATTGCTCAATCAATCGTATATGCACGAAATAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAACAATGC
TGTTGAAGGTGCTGCAGATAGTTACTTGAAACTAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAAGACTTATTTGCCTTAGGTTTCTCTACCAAAGGAAGAAACAGA
GGTCTAGGACTTAATAATGTCAAAGAGATCTTAGATAAGTATGACAACATTATTTTAGAAACAGAAATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGAGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

74.83

100

0.752
  comD/comD2 Streptococcus pneumoniae TIGR4

73.923

100

0.743
  comD Streptococcus mitis NCTC 12261

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae R6

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae Rx1

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae D39

73.469

100

0.738
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.733

85.194

0.424
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.649

0.421