Detailed information NTG0690157

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: C822_RS08395
• Genome accession: NZ_CP097561
• Coordinates: 1676935..1677672 (+)
• Length: 245 a.a.
• NCBI ID: WP_004049924.1
• Uniprot ID: A0AAE6WG22
• Organism: Ligilactobacillus murinus ASF361
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1671935..1682672

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C822_RS08370 (C822_001682)	-	1672265..1673257 (+)	993	WP_004049916.1	LacI family DNA-binding transcriptional regulator	-
C822_RS08375 (C822_001683)	rbsK	1673365..1674270 (+)	906	WP_004049918.1	ribokinase	-
C822_RS08380 (C822_001684)	rbsD	1674289..1674684 (+)	396	WP_004049920.1	D-ribose pyranase	-
C822_RS08385 (C822_001685)	-	1674702..1675589 (+)	888	WP_004049921.1	GRP family sugar transporter	-
C822_RS08390 (C822_001686)	-	1675861..1676823 (-)	963	WP_004048827.1	IS30 family transposase	-
C822_RS08395 (C822_001687)	comE/blpR	1676935..1677672 (+)	738	WP_004049924.1	LytTR family DNA-binding domain-containing protein	Regulator
C822_RS08400 (C822_001688)	-	1677687..1679012 (+)	1326	WP_004049925.1	GHKL domain-containing protein	-
C822_RS08405 (C822_001689)	-	1679536..1680381 (+)	846	WP_004049928.1	ABC transporter ATP-binding protein	-
C822_RS08410 (C822_001690)	-	1680374..1681087 (+)	714	WP_004049931.1	ABC transporter permease	-
C822_RS08415 (C822_001691)	-	1681294..1682442 (+)	1149	WP_004049932.1	hypothetical protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28239.61 Da
• Isoelectric Point: 5.9838

>NTDB_id=690157 C822_RS08395 WP_004049924.1 1676935..1677672(+) (comE/blpR) [Ligilactobacillus murinus ASF361]
MINIFVLEDEILQQSRIETAILKILNEEQIKCRVFDVFGSSSQLLEAIEERGGHQLFFLDIEIKDEEKKGLEIAKEIRKK
DPAATIVFVTTHSEFMPLTFKFKVSALDFIDKALGEQYFYERIKSAIDYTLASAGETLSQESFHLETSLSQIQVPLKKIL
YFETSPTVHKVILHTIDERIEFYATISEIEKKDSRLYRSHKSFVVNPANIERLDKVNKIIYFPNGDSCLVARTKLKGLSE
RITLL

Nucleotide

• Length: 738 bp

>NTDB_id=690157 C822_RS08395 WP_004049924.1 1676935..1677672(+) (comE/blpR) [Ligilactobacillus murinus ASF361]
ATGATCAATATTTTTGTACTTGAAGATGAGATACTTCAACAGTCTCGCATTGAAACGGCCATTCTAAAAATTTTAAACGA
AGAACAGATAAAGTGTAGAGTTTTTGATGTTTTTGGAAGCTCTTCTCAATTGTTAGAAGCTATTGAGGAGAGAGGGGGGC
ACCAGTTATTTTTCCTAGATATTGAAATTAAGGACGAGGAGAAAAAAGGACTGGAGATCGCTAAGGAGATCCGAAAAAAA
GATCCCGCTGCGACTATCGTTTTTGTGACGACGCATTCGGAATTTATGCCACTAACATTTAAATTTAAAGTTAGTGCTCT
TGATTTTATCGATAAAGCTTTAGGAGAGCAATACTTCTATGAGCGTATTAAATCTGCTATTGACTACACACTAGCTAGTG
CTGGAGAAACGCTGTCTCAAGAATCATTTCATTTAGAAACGTCACTATCTCAAATACAAGTGCCTTTAAAAAAAATCCTG
TATTTTGAAACATCCCCGACTGTACATAAGGTTATTTTGCATACGATCGATGAACGAATTGAATTTTATGCAACGATCTC
TGAGATCGAAAAAAAAGACAGCCGATTATATAGAAGCCATAAGTCATTTGTAGTAAATCCTGCTAACATTGAGCGTCTGG
ATAAGGTCAATAAGATCATTTATTTTCCAAATGGAGATTCTTGTTTAGTAGCACGAACAAAACTTAAAGGATTAAGTGAA
AGGATTACATTATTGTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.23	97.551	0.539
comE/comE1	Streptococcus equinus JB1	47.521	98.776	0.469
comE/comE2	Streptococcus equinus JB1	41.736	98.776	0.412
comE/comE2	Streptococcus gordonii strain NCTC7865	39.754	99.592	0.396
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.754	99.592	0.396
comE	Streptococcus pneumoniae R6	37.037	99.184	0.367
comE	Streptococcus pneumoniae TIGR4	37.037	99.184	0.367
comE	Streptococcus mitis NCTC 12261	37.037	99.184	0.367
comE	Streptococcus mitis SK321	37.037	99.184	0.367
comE	Streptococcus pneumoniae Rx1	37.037	99.184	0.367
comE	Streptococcus pneumoniae D39	37.037	99.184	0.367
comE	Streptococcus infantis strain Atu-4	36.626	99.184	0.363