Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   MLL77_RS17890 Genome accession   NZ_CP097209
Coordinates   3893960..3895201 (+) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain W3     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3888960..3900201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MLL77_RS17865 (MLL77_17830) ampD 3889333..3889905 (-) 573 WP_039040507.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  MLL77_RS17870 (MLL77_17835) - 3890034..3890504 (+) 471 WP_042015101.1 retropepsin-like aspartic protease -
  MLL77_RS17875 (MLL77_17840) nadC 3890508..3891371 (+) 864 WP_041213995.1 carboxylating nicotinate-nucleotide diphosphorylase -
  MLL77_RS17880 (MLL77_17845) - 3891682..3892122 (+) 441 WP_274799056.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MLL77_RS17885 (MLL77_17850) pilB 3892126..3893832 (+) 1707 WP_274799055.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  MLL77_RS17890 (MLL77_17855) pilC 3893960..3895201 (+) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  MLL77_RS17895 (MLL77_17860) pilD 3895279..3896154 (+) 876 WP_182976107.1 A24 family peptidase Machinery gene
  MLL77_RS17900 (MLL77_17865) coaE 3896173..3896787 (+) 615 WP_048208563.1 dephospho-CoA kinase -
  MLL77_RS17905 (MLL77_17870) zapD 3896825..3897547 (+) 723 WP_010675825.1 cell division protein ZapD -
  MLL77_RS17910 (MLL77_17875) yacG 3897558..3897752 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  MLL77_RS17915 (MLL77_17880) mutT 3897810..3898214 (-) 405 WP_174213873.1 8-oxo-dGTP diphosphatase MutT -
  MLL77_RS17920 (MLL77_17885) - 3898223..3899407 (-) 1185 WP_282414465.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=687836 MLL77_RS17890 WP_010675822.1 3893960..3895201(+) (pilC) [Aeromonas caviae strain W3]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=687836 MLL77_RS17890 WP_010675822.1 3893960..3895201(+) (pilC) [Aeromonas caviae strain W3]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTTTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACTATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCTCGCGGCCACGAGAAAGCGGC
TGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACAGGTACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCTC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCTGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCCCTGGTCTCGGCGGCAGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGACCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375