Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   SNAG_RS09700 Genome accession   NZ_AP017652
Coordinates   1921435..1921560 (-) Length   41 a.a.
NCBI ID   WP_096408765.1    Uniprot ID   A0A1E1GDC8
Organism   Streptococcus sp. NPS 308     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916435..1926560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS09675 (SNAG_1894) - 1918563..1919105 (+) 543 WP_061407778.1 TetR-like C-terminal domain-containing protein -
  SNAG_RS09690 (SNAG_1897) comE 1919346..1920098 (-) 753 WP_000866077.1 competence system response regulator transcription factor ComE Regulator
  SNAG_RS09695 (SNAG_1898) comD 1920095..1921414 (-) 1320 WP_096408763.1 competence system sensor histidine kinase ComD Regulator
  SNAG_RS09700 (SNAG_1899) comC/comC2 1921435..1921560 (-) 126 WP_096408765.1 competence-stimulating peptide ComC Regulator
  SNAG_RS09710 (SNAG_1901) rlmH 1921841..1922320 (-) 480 WP_096408768.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SNAG_RS09715 (SNAG_1902) htrA 1922506..1923696 (+) 1191 WP_096408770.1 S1C family serine protease Regulator
  SNAG_RS09720 (SNAG_1903) spo0J 1923754..1924512 (+) 759 WP_004239627.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4990.76 Da        Isoelectric Point: 10.3052

>NTDB_id=68383 SNAG_RS09700 WP_096408765.1 1921435..1921560(-) (comC/comC2) [Streptococcus sp. NPS 308]
MKNTVKLEQFKEVTETELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=68383 SNAG_RS09700 WP_096408765.1 1921435..1921560(-) (comC/comC2) [Streptococcus sp. NPS 308]
ATGAAAAACACAGTTAAATTGGAACAATTTAAAGAGGTAACAGAAACAGAATTGCAGGAGATTCGAGGTGGGGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GDC8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

56.098

100

0.561
  comC/comC2 Streptococcus pneumoniae TIGR4

56.098

100

0.561
  comC Streptococcus mitis SK321

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae R6

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae G54

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae D39

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae Rx1

53.659

100

0.537
  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463
  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39
  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366

Multiple sequence alignment