Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   SNAG_RS09695 Genome accession   NZ_AP017652
Coordinates   1920095..1921414 (-) Length   439 a.a.
NCBI ID   WP_096408763.1    Uniprot ID   A0A1E1GDH1
Organism   Streptococcus sp. NPS 308     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1915095..1926414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS09670 (SNAG_1893) - 1915780..1918434 (-) 2655 WP_096408760.1 YhgE/Pip domain-containing protein -
  SNAG_RS09675 (SNAG_1894) - 1918563..1919105 (+) 543 WP_061407778.1 TetR-like C-terminal domain-containing protein -
  SNAG_RS09690 (SNAG_1897) comE 1919346..1920098 (-) 753 WP_000866077.1 competence system response regulator transcription factor ComE Regulator
  SNAG_RS09695 (SNAG_1898) comD 1920095..1921414 (-) 1320 WP_096408763.1 competence system sensor histidine kinase ComD Regulator
  SNAG_RS09700 (SNAG_1899) comC/comC2 1921435..1921560 (-) 126 WP_096408765.1 competence-stimulating peptide ComC Regulator
  SNAG_RS09710 (SNAG_1901) rlmH 1921841..1922320 (-) 480 WP_096408768.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SNAG_RS09715 (SNAG_1902) htrA 1922506..1923696 (+) 1191 WP_096408770.1 S1C family serine protease Regulator
  SNAG_RS09720 (SNAG_1903) spo0J 1923754..1924512 (+) 759 WP_004239627.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51168.08 Da        Isoelectric Point: 6.6917

>NTDB_id=68382 SNAG_RS09695 WP_096408763.1 1920095..1921414(-) (comD) [Streptococcus sp. NPS 308]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKGIFISLLLSLLYHSTHTFISVTLSSITGDEVVLHYKSTFLLVVLLMTYFSILVIIRYFHLEIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILAAIIFICLLLCFFAMNSYKVQVEKEIALKQKKFEQKYLQTYTDEIVGLYNE
IRGFRHDYAGMLVSMQMAIDSEDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARNNDVEFTL
EVKDVITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSENLFALGFSTKGRNR
GLGLNNVNEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=68382 SNAG_RS09695 WP_096408763.1 1920095..1921414(-) (comD) [Streptococcus sp. NPS 308]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGGAATTTTTATCAGTTTACTATTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACTTTATCTTC
TATAACAGGAGATGAAGTAGTATTACACTATAAGAGTACATTCCTTTTAGTAGTATTGTTGATGACTTATTTTTCTATTC
TAGTAATAATTCGTTATTTTCATCTGGAAATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTGCATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTAGCAGCCATCATTTTTATATGTTTATTACTGTGCTTCTTCGCAATGAACTCTTATAAGGTTCAAGTTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGTATTTACAGACTTATACAGATGAAATTGTAGGTTTGTATAATGAA
ATTCGAGGTTTTCGTCATGATTATGCAGGTATGCTTGTCAGCATGCAAATGGCAATTGACAGTGAAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTATTAGTAAAAGCGAATCAAAAACTGCGTTCAGAGAAATATACTTACTTTGATTTGAATA
ATATAGAAGATTCAGCTTTACGTAGTTTGATTGCTCAATCCATTGTCTATGCACGAAATAATGATGTAGAGTTTACATTG
GAAGTAAAGGATGTTATTACTAGATTGTCAATAGATTTACTTGATCTTGTTCGCATCATGAGCATTCTCTTAAATAATGC
TGTTGAAGGTGCTGCGGATAGTTACTTGAAACAAATGGAAGTTGCAGTTATTAAAATGGATTTTGAAACAGTTATAGTCA
TCCAGAATTCATGTAAAATCACTATGACGCCTTCAGAAAACTTATTTGCCTTAGGTTTCTCTACTAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAATGAGATTTTAGACAAGTATGACAACATTATTCTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GDH1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

73.923

100

0.743
  comD/comD2 Streptococcus pneumoniae TIGR4

73.696

100

0.74
  comD Streptococcus mitis NCTC 12261

73.696

100

0.74
  comD/comD1 Streptococcus pneumoniae Rx1

73.243

100

0.736
  comD/comD1 Streptococcus pneumoniae D39

73.243

100

0.736
  comD/comD1 Streptococcus pneumoniae R6

73.243

100

0.736
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.733

85.194

0.424
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.649

0.421

Multiple sequence alignment